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用正丁基氰基丙烯酸酯进行选择性动脉栓塞治疗胸椎动脉瘤样骨囊肿:一例报告

Selective arterial embolization with n-butyl cyanoacrylate in the treatment of aneursymal bone cyst of the thoracic vertebra: a case report.

作者信息

Marushima Aiki, Matsumaru Yuji, Suzuki Kensuke, Takigawa Tomoji, Kujiraoka Yuji, Anno Izumi, Matsumura Akira

机构信息

Department of Neurosurgery, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.

出版信息

Spine (Phila Pa 1976). 2009 Mar 15;34(6):E230-4. doi: 10.1097/BRS.0b013e31818f8f7c.

Abstract

STUDY DESIGN

A case report of aneurysmal bone cyst of the mobile spine.

OBJECTIVE

To present a pediatric case of aneurysmal bone cyst (ABC) of the mobile spine treated successfully by selective arterial embolization (SAE) with n-butyl cyanoacrylate (NBCA).

SUMMARY OF BACKGROUND DATA

The endovascular treatment is an important treatment option for the ABC of the mobile spine. However, there are few reported case treated by SAE with NBCA.

METHODS

A 12-year-old healthy boy was introduced with a complaint of back pain. Computed tomography showed an osteolytic expanding mass in the pedicle, lamina, and spinous process on the level of T10. Magnetic resonance imaging revealed a multicystic mass with fluid-fluid levels that extended into the spinal canal and compressed the spinal cord from the dorsal side. Digital subtraction angiography showed an abnormal blood supply from the posterior spinal branch of the left T9 artery. An abnormal mass was diagnosed as an ABC based on these neuroradiologic examinations.

RESULT

The patient underwent SAE with NBCA (Histoacryl, B. Braun, Melsungen, Germany) diluted with Lipiodol (Laboratorie Guerbet, France) in a rate of 1:4. Computed tomography performed 1 month after treatment revealed partial ossification of the bone cortex. MR imaging showed shrinkage of the cyst and decompression of the spinal cord. Back pain of the patient disappeared and the shrunken cyst was stable without recurrence during the 3-year follow-up period.

CONCLUSION

SAE in a pediatric case with ABC of the mobile spine was effective in improving of clinical symptom and shrinking of the cyst.

摘要

研究设计

活动脊柱动脉瘤样骨囊肿的病例报告。

目的

介绍一例通过用正丁基氰基丙烯酸酯(NBCA)进行选择性动脉栓塞(SAE)成功治疗的活动脊柱动脉瘤样骨囊肿(ABC)的儿科病例。

背景资料总结

血管内治疗是活动脊柱ABC的重要治疗选择。然而,很少有报道用NBCA进行SAE治疗的病例。

方法

一名12岁健康男孩因背痛就诊。计算机断层扫描显示T10水平的椎弓根、椎板和棘突有溶骨性膨胀性肿块。磁共振成像显示一个有多房性肿块且有液-液平面,延伸至椎管并从背侧压迫脊髓。数字减影血管造影显示来自左T9动脉脊髓后支的异常血供。基于这些神经放射学检查,一个异常肿块被诊断为ABC。

结果

患者接受了用碘油(法国Guerbet实验室)以1:4比例稀释的NBCA(Histoacryl,德国贝朗医疗公司,梅尔松根)进行的SAE。治疗后1个月进行的计算机断层扫描显示骨皮质部分骨化。磁共振成像显示囊肿缩小且脊髓减压。患者的背痛消失,在3年随访期内缩小的囊肿稳定且无复发。

结论

在活动脊柱ABC的儿科病例中,SAE在改善临床症状和囊肿缩小方面是有效的。

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