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非裔美国人和高加索人中髋部症状、影像学及症状性髋骨关节炎的患病率:约翰斯顿县骨关节炎项目

Prevalence of hip symptoms and radiographic and symptomatic hip osteoarthritis in African Americans and Caucasians: the Johnston County Osteoarthritis Project.

作者信息

Jordan Joanne M, Helmick Charles G, Renner Jordan B, Luta Gheorghe, Dragomir Anca D, Woodard Janice, Fang Fang, Schwartz Todd A, Nelson Amanda E, Abbate Lauren M, Callahan Leigh F, Kalsbeek William D, Hochberg Marc C

机构信息

Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, CB 7280, 3300 Thurston Building, Chapel Hill, NC 27599-7280, USA.

出版信息

J Rheumatol. 2009 Apr;36(4):809-15. doi: 10.3899/jrheum.080677. Epub 2009 Mar 13.

Abstract

OBJECTIVE

To report contemporary estimates of the prevalence of hip-related osteoarthritis (OA) outcomes in African Americans and Caucasians aged>or=45 years.

METHODS

Weighted prevalence estimates and their corresponding 95% confidence intervals for hip symptoms, radiographic hip OA, symptomatic hip OA, and severe radiographic hip OA were calculated using SUDAAN for age, race, and sex subgroups among 3068 participants (33% African Americans, 38% men) in the baseline examination (1991-97) of The Johnston County Osteoarthritis Project, a population-based study of OA in North Carolina. Radiographic hip OA was defined as Kellgren-Lawrence radiographic grade>or=2, moderate/severe radiographic hip OA as grades 3 and 4, and symptomatic hip OA as hip symptoms in a hip with radiographic OA.

RESULTS

Hip symptoms were present in 36%; 28% had radiographic hip OA; nearly 10% had symptomatic hip OA; and 2.5% had moderate/severe radiographic hip OA. Prevalence of all 4 outcomes was higher in older individuals; most outcomes were higher for women and African Americans.

CONCLUSION

African Americans in this population do not have a lower prevalence of hip-related OA outcomes as previous studies suggested. Increasing public and health system awareness of the relatively high prevalence of these outcomes, which can be disabling, may help to decrease their effects and ultimately prevent them.

摘要

目的

报告年龄≥45岁的非裔美国人和高加索人中与髋关节相关的骨关节炎(OA)结局的当代患病率估计值。

方法

在约翰斯顿县骨关节炎项目的基线检查(1991 - 1997年)中,对3068名参与者(33%为非裔美国人,38%为男性)按年龄、种族和性别亚组,使用SUDAAN计算髋关节症状、髋关节X线骨关节炎、症状性髋关节OA和严重髋关节X线骨关节炎的加权患病率估计值及其相应的95%置信区间。该项目是北卡罗来纳州一项基于人群的OA研究。髋关节X线骨关节炎定义为凯尔格伦 - 劳伦斯X线分级≥2级,中度/重度髋关节X线骨关节炎为3级和4级,症状性髋关节OA为存在X线骨关节炎的髋关节出现髋关节症状。

结果

36%的人存在髋关节症状;28%的人有髋关节X线骨关节炎;近10%的人有症状性髋关节OA;2.5%的人有中度/重度髋关节X线骨关节炎。所有这4种结局的患病率在老年人中更高;大多数结局在女性和非裔美国人中更高。

结论

该人群中的非裔美国人与髋关节相关的OA结局患病率并不像之前研究所表明的那样低。提高公众和卫生系统对这些可能导致残疾的结局相对较高患病率的认识,可能有助于减轻其影响并最终预防这些结局。

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