Chapman Erin M, Ranger Adrianna, Lee Donald H, Hammond Robert R
Department of Clinical Neurologic Sciences, London Health Sciences Center and Schlich School of Medicine and Dentistry, London, Ontario, Canada.
Brain Pathol. 2009 Apr;19(2):349-52. doi: 10.1111/j.1750-3639.2009.00281.x.
A 15 year old male presented with hydrocephalus from a tectal mass obstructing the cerebral aqueduct and upper fourth ventricle. The solid-cystic partly enhancing mass proved to be a pigmented pleomorphic xanthoastrocytoma, the third such example reported. The lesion revealed typical features of a PXA with the unusual addition of intracytoplasmic melanin in select lesional cells. Melanin pigment production is uncommon in glial tumors and of uncertain significance. The present case is recurrence-free one year post-operatively.
一名15岁男性因中脑顶盖肿物阻塞大脑导水管和第四脑室上部而出现脑积水。实性囊性部分强化的肿物经证实为色素性多形性黄色星形细胞瘤,这是报道的第三例此类病例。该病变显示出PXA的典型特征,在部分病变细胞中异常地出现了胞浆内黑色素。黑色素生成在神经胶质肿瘤中并不常见,其意义尚不确定。本例患者术后一年无复发。