Division of Neurological Science, University of Liverpool, UK.
Neuropsychiatr Dis Treat. 2007 Feb;3(1):117-31. doi: 10.2147/nedt.2007.3.1.117.
Patient adherence to medication continues to be a cause of concern within the medical profession. This review examines the various methods of quantifying the level of patient adherence, progress in predicting causes of non-adherence, and the implications for its management. Contributions from the medical, health belief, and psychosocial models are discussed in order to highlight how the concept of adherence has changed over time. The impact of epilepsy, seizures, and taking antiepileptic drugs (AEDs) on both adherence and quality of life are also explored. The volume and quality of previous research conducted has enabled a number of predictive factors to be identified, from which various strategies have been developed. While this review concentrates on potential strategies in managing treatment adherence within epilepsy, findings can equally be applied to other chronic conditions.
患者对药物的依从性仍然是医学界关注的一个问题。本综述考察了量化患者依从性水平的各种方法、预测不依从原因的进展,以及对其管理的影响。讨论了医学、健康信念和心理社会模型的贡献,以强调依从性概念随时间的变化。还探讨了癫痫、癫痫发作和服用抗癫痫药物(AEDs)对依从性和生活质量的影响。以前的研究数量和质量使得能够确定一些预测因素,从中制定了各种策略。虽然本综述集中在管理癫痫治疗依从性方面的潜在策略,但这些发现同样适用于其他慢性疾病。