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一项针对择期手术患者的戒烟计划的疗效:一项随机临床试验。

The efficacy of a smoking cessation programme in patients undergoing elective surgery: a randomised clinical trial.

作者信息

Sadr Azodi O, Lindström D, Adami J, Tønnesen H, Nåsell H, Gilljam H, Wladis A

机构信息

Department of Medicine, Clinical Epidemiology Unit, Karolinska Institute, Stockholm, Sweden.

出版信息

Anaesthesia. 2009 Mar;64(3):259-65. doi: 10.1111/j.1365-2044.2008.05758.x.

Abstract

It is known that smokers constitute an important risk group of patients undergoing surgery. It is unknown how smoking cessation intervention initiated 4 weeks prior to elective surgery affects the probability of permanent cessation. We randomly assigned 117 patients, scheduled to undergo elective orthopaedic and general surgery, to smoking cessation intervention and control group. The intervention group underwent a programme initiated, on average, 4 weeks prior to surgery with weekly meetings or telephone counselling and were provided with free nicotine replacement therapy (NRT). The control group received standard care. As a result, 20/55 (36%) patients the intervention group vs 1/62 (2%) in the control group became completely abstinent throughout the peri-operative period (p < 0.001). After 1 year, those in the intervention group was most likely to be abstinent (18/55 (33%) vs 9/62 (15%) of the controls (p = 0.03). Level of nicotine dependence and obesity seemed to be a predictor of long-term abstinence (p = 0.02).

摘要

众所周知,吸烟者是接受手术患者中的一个重要风险群体。术前4周开始的戒烟干预对永久戒烟概率有何影响尚不清楚。我们将117例计划接受择期骨科和普外科手术的患者随机分为戒烟干预组和对照组。干预组平均在手术前4周开始一项计划,每周开会或电话咨询,并提供免费尼古丁替代疗法(NRT)。对照组接受标准护理。结果,干预组20/55(36%)的患者与对照组1/62(2%)的患者在围手术期完全戒烟(p<0.001)。1年后,干预组患者最有可能戒烟(18/55(33%),而对照组为9/62(15%)(p=0.03)。尼古丁依赖程度和肥胖似乎是长期戒烟的一个预测因素(p=0.02)。

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