Hwang Shin, Lee Sung-Gyu, Ahn Chul-Soo, Kim Ki-Hun, Moon Deok-Bog, Ha Tae-Yong, Song Gi-Won, Jung Dong-Hwan, Ryu Je-Ho, Ko Kyung-Hoon, Choi Nam-Kyu, Kim Kwan-Woo
Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Liver Transpl. 2009 Apr;15(4):427-34. doi: 10.1002/lt.21697.
This study was intended to describe in detail the surgical technique and long-term outcome of autologous portal vein (PV) Y-graft interposition for adult living donor liver transplantation (LDLT). We assessed the outcome of 841 patients who underwent right lobe LDLT from January 2002 to December 2007 with respect to the reconstruction of double-graft PVs. PV anatomy of the donor livers was classified as type I in 796 patients (94.6%), type II in 15 patients (1.8%), and type III in 30 patients (3.6%). Seven type II grafts and all type III PV grafts had double PV orifices. Autologous PV Y-graft interposition was used in 31 patients, and complications occurred in only 1 patient during a median follow-up of 27 months. Overall, the 1- and 3-year graft survival rates were 87.5% and 80.6%, respectively. Use of a Y-graft was not a risk factor for biliary complications, but the liver anatomy of anomalous PV per se seems to be associated with a higher occurrence of biliary complications, especially during the early posttransplant period. The favorable outcome and technical feasibility of autologous portal Y-graft interposition imply that this technique could be the standard procedure for reconstruction of right lobe grafts with double PV orifices.
本研究旨在详细描述成人活体肝移植(LDLT)中自体门静脉(PV)Y形移植插入术的手术技术及长期疗效。我们评估了2002年1月至2007年12月期间接受右半肝LDLT的841例患者双移植PV重建的疗效。供肝的PV解剖结构在796例患者中分类为I型(94.6%),15例患者中为II型(1.8%),30例患者中为III型(3.6%)。7例II型移植物和所有III型PV移植物有双PV开口。31例患者采用自体PV Y形移植插入术,中位随访27个月期间仅1例发生并发症。总体而言,1年和3年移植物存活率分别为87.5%和80.6%。使用Y形移植物不是胆系并发症的危险因素,但异常PV本身的肝脏解剖结构似乎与胆系并发症的较高发生率相关,尤其是在移植后早期。自体门静脉Y形移植插入术的良好疗效和技术可行性表明,该技术可能成为双PV开口右半肝移植物重建的标准术式。