Department of Education in Science and Mathematics, Regional Institute of Education, National Council of Educational Research and Training, Mysore, 570006, India.
Biol Trace Elem Res. 2009 Dec;131(3):255-62. doi: 10.1007/s12011-009-8371-4. Epub 2009 Apr 8.
Element contents of teeth elucidate exposure nature, but less is known about association of tooth element concentrations of diabetics and hypertensives with exposure profile. Present study aims to estimate copper, chromium, iron, zinc, nickel, and lead concentrations in the permanent teeth of control, diabetic, and hypertensive subjects from Mysore. The results show that lead levels of teeth (Pb-T) are higher in the hypertensives and diabetics, whereas copper levels of teeth (Cu-T) are lower in the hypertensives and users of stainless steel utensils than that of controls and users of mixed utensils. The elevated Cu-T levels found in the users of mixed utensils that being made of several metals are ascribed to leaching effect of sour and spicy food of Indian cuisine. The element levels were influenced by diet (Zn-T), place of living, sex and income (Pb-T) of the subjects, but not by age, drinking water from different sources, and certain habits viz., smoking, alcohol consumption, chewing betel, and nut. Thus, it is evident that high Pb-T and low Cu-T levels may be related with diabetes and hypertension and high Pb-T and Cu-T levels, respectively, in the urbanites, and the users of mixed utensils may show different exposure profiles from environment and utensils.
牙齿中的元素含量可以说明暴露的性质,但对于糖尿病患者和高血压患者牙齿中元素浓度与暴露情况的关联知之甚少。本研究旨在评估来自迈索尔的对照组、糖尿病组和高血压组的恒牙中的铜、铬、铁、锌、镍和铅的浓度。结果表明,高血压患者和糖尿病患者的牙齿中的铅水平(Pb-T)较高,而高血压患者和不锈钢餐具使用者的牙齿中的铜水平(Cu-T)低于对照组和混合餐具使用者。在使用由多种金属制成的混合餐具的人群中发现的升高的 Cu-T 水平归因于印度菜酸辣食物的浸出效应。元素水平受受试者的饮食(Zn-T)、居住地点、性别和收入(Pb-T)的影响,但不受年龄、饮用水源和某些习惯(如吸烟、饮酒、咀嚼槟榔和坚果)的影响。因此,很明显,高 Pb-T 和低 Cu-T 水平可能与糖尿病和高血压有关,而城市居民中高 Pb-T 和 Cu-T 水平可能分别与环境和餐具有关,使用混合餐具的人群可能显示出不同的暴露模式。