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病例匹配的腹腔镜辅助与开放性直肠结肠全切除术的疗效比较

Outcomes for case-matched laparoscopically assisted versus open restorative proctocolectomy.

作者信息

El-Gazzaz G S, Kiran R P, Remzi F H, Hull T L, Geisler D P

机构信息

Department of Colorectal Surgery, A30, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA.

出版信息

Br J Surg. 2009 May;96(5):522-6. doi: 10.1002/bjs.6578.

Abstract

BACKGROUND

The aim of this study was to compare safety, early and late outcomes, quality of life and functional results of laparoscopically assisted versus open ileal pouch-anal anastomosis (IPAA).

METHODS

Patients who had laparoscopically assisted IPAA between 1992 and 2007 were identified from a database and retrospectively matched for age, sex, body mass index (BMI) and operation date to patients who had open IPAA at a ratio of 1:2. Intraoperative, postoperative and long-term functional outcomes were compared. Quality of life was determined by the Cleveland Global Quality of Life scale at 1 and 5 years.

RESULTS

A total of 119 patients (59 men, 60 women; mean(s.d) age 35.5(14.2) years, BMI 24.7(5.0) kg/m(2)) had laparoscopically assisted IPAA, with conversion in nine patients (7.6 per cent); these were compared with 238 patients who had open IPAA. The 30-day and long-term results were similar, as well as quality of life at 1 and 5 years, except that patients in the laparoscopic group had shorter median time to stoma action (2 versus 3 days; P = 0.001) and marginally shorter hospital stay. Median operating times were longer in the laparoscopic group (272 versus 163 min; P = 0.040).

CONCLUSION

Laparoscopically assisted IPAA had similar outcomes to open IPAA, but with some short-term advantages.

摘要

背景

本研究旨在比较腹腔镜辅助回肠储袋肛管吻合术(IPAA)与开放性IPAA的安全性、早期和晚期疗效、生活质量及功能结果。

方法

从数据库中识别出1992年至2007年间接受腹腔镜辅助IPAA的患者,并根据年龄、性别、体重指数(BMI)和手术日期,以1:2的比例与接受开放性IPAA的患者进行回顾性匹配。比较术中、术后及长期功能结果。通过克利夫兰全球生活质量量表在1年和5年时测定生活质量。

结果

共有119例患者(59例男性,60例女性;平均(标准差)年龄35.5(14.2)岁,BMI 24.7(5.0)kg/m²)接受了腹腔镜辅助IPAA,其中9例(7.6%)中转开腹;将这些患者与238例接受开放性IPAA的患者进行比较。30天和长期结果相似,1年和5年时的生活质量也相似,只是腹腔镜组患者造口排气的中位时间较短(2天对3天;P = 0.001),住院时间略短。腹腔镜组的中位手术时间较长(272分钟对163分钟;P = 0.040)。

结论

腹腔镜辅助IPAA与开放性IPAA的结果相似,但具有一些短期优势。

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