Harel Ziv, Perl Jeff, Herzenberg Andrew M, Bargman Joanne M
Department of Medicine, Division of Nephrology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Am J Kidney Dis. 2009 Sep;54(3):533-7. doi: 10.1053/j.ajkd.2009.01.272. Epub 2009 Apr 19.
Inflammatory myofibroblastic tumor, or inflammatory pseudotumor, usually is a benign lesion composed of mixed inflammatory and fibroblastic elements. It has rarely been reported in the posttransplantation setting and never in association with a renal allograft. Although the pathogenesis of this lesion is unclear, exposure to immunosuppressive agents and various infections have been implicated in its development. We report the first case of inflammatory myofibroblastic tumor infiltrating a renal allograft and highlight the role immunosuppression may have in the development of this lesion.