Wang Yan, Ma Lizhuang, Liu Ping
Department of Computer Science & Engineering, Shanghai Jiao Tong University, Shanghai, China.
Comput Methods Programs Biomed. 2009 Sep;95(3):249-57. doi: 10.1016/j.cmpb.2009.03.004. Epub 2009 Apr 19.
Traditional Chinese medicine (TCM) treatment is one of the safe and effective methods for liver cirrhosis. In the process of its treatment, a very important step, syndrome prediction is generally performed by physicians at present, which actually hinders the application prospects of TCM. Based on the data mining algorithm, a novel method called TCMSP (traditional Chinese medicine syndrome prediction) is proposed, which consists of two phases. In the first phase, based on an improved information gain method in multi-view, the critical features are filtered from the original features. In the second phase, the class label of a new case is predicted automatically based on accuracy-weighted majority voting. The proposed method is evaluated by the liver cirrhosis dataset, 20 critical features are selected from original 105 features and the corresponding syndromes of 138 new cases are identified respectively. The critical features are in sound agreement with those used by the physicians in making their clinical decisions. Finally, this new method is also demonstrated on three standard datasets (SPECT Heart, Lung Cancer and Iris) and the results are compared with some other methods. The experimental results show that TCMSP method performs well in the field of TCM diagnosis.
中医治疗是肝硬化安全有效的方法之一。在其治疗过程中,目前综合征预测这一非常重要的步骤通常由医生进行,这实际上阻碍了中医的应用前景。基于数据挖掘算法,提出了一种名为TCMSP(中医综合征预测)的新方法,该方法包括两个阶段。在第一阶段,基于多视图中改进的信息增益方法,从原始特征中筛选出关键特征。在第二阶段,基于准确率加权多数投票自动预测新病例的类别标签。利用肝硬化数据集对所提方法进行评估,从原始的105个特征中选出20个关键特征,并分别识别出138例新病例的相应综合征。这些关键特征与医生在临床决策中使用的特征高度一致。最后,在三个标准数据集(SPECT心脏、肺癌和鸢尾花)上对该新方法进行了验证,并将结果与其他一些方法进行了比较。实验结果表明,TCMSP方法在中医诊断领域表现良好。