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腹腔镜袖状胃切除术后吻合口漏的非手术治疗。

Nonsurgical treatment of staple line leaks after laparoscopic sleeve gastrectomy.

机构信息

Department of Medical and Surgical Digestive Diseases, University La Sapienza, Viale del Policlinico, 00161, Rome, Italy.

出版信息

Obes Surg. 2009 Jul;19(7):821-6. doi: 10.1007/s11695-009-9840-8. Epub 2009 Apr 21.

Abstract

BACKGROUND

Laparoscopic sleeve gastrectomy (LSG) is gaining popularity as a "per se" bariatric procedure due to its effectiveness on weight loss and comorbidity resolution. The most feared and life-threatening complication after LSG is the staple line leak and its management is still a debated issue. Aim of this paper is to analyze the incidence of leak and the treatment solutions adopted in a consecutive series of 200 LSG.

METHODS

From October 2002 to November 2008, 200 patients underwent LSG. Nineteen patients (9.5%) had a body mass index (BMI) of >60 kg/m(2). A 48-Fr bougie is used to obtain an 80-120-ml gastric pouch. An oversewing running suture to reinforce the staple line was performed in the last 100 cases. The technique adopted to reinforce the staple line is a running suture taken through and through the complete stomach wall.

RESULTS

Staple line leaks occurred in six patients (mean BMI 52.5; mean age 41.6 years). Leak presentation was early in three cases (first, second, and third postoperative (PO) day), late in the remaining three cases (11th, 22nd, and 30th PO day). The most common leak location was at the esophagogastric junction (five cases). Mortality was nihil. Nonoperative management (total parenteral nutrition, proton pump inhibitor, and antibiotics) was adopted in all cases. Percutaneous abdominal drainage was placed in five patients. In one case, a small fistula was successfully treated by endoscopic injection of fibrin glue only. Self-expandable covered stent was used in three cases. Complete healing of leaks was obtained in all patients (mean healing time 71 days).

CONCLUSION

Nonoperative treatment (percutaneous drainage, endoscopy, stent) is feasible, safe, and effective for staple line leaks in patients undergoing LSG; furthermore, it may avoid more mutilating procedures such as total gastrectomy.

摘要

背景

腹腔镜袖状胃切除术(LSG)因其在减重和并发症解决方面的有效性而作为一种“本身”的减重手术而受到关注。LSG 后最可怕和危及生命的并发症是吻合口漏,其处理仍然是一个有争议的问题。本文旨在分析连续 200 例 LSG 中吻合口漏的发生率及采用的治疗方法。

方法

2002 年 10 月至 2008 年 11 月,200 例患者接受了 LSG。19 例(9.5%)患者的体重指数(BMI)>60kg/m²。使用 48Fr 探条获得 80-120ml 的胃袋。在最后 100 例中,采用连续缝合加固吻合口。加固吻合口的技术是采用连续缝线穿过整个胃壁。

结果

6 例(平均 BMI 52.5;平均年龄 41.6 岁)患者发生吻合口漏。3 例患者表现为早期(术后第 1、2 和 3 天),其余 3 例患者为晚期(术后第 11、22 和 30 天)。最常见的漏口部位是食管胃连接部(5 例)。无死亡病例。所有患者均采用非手术治疗(全胃肠外营养、质子泵抑制剂和抗生素)。5 例患者放置了经皮腹腔引流。1 例小瘘口仅用内镜注射纤维蛋白胶成功治疗。3 例患者使用了自膨式覆膜支架。所有患者(平均愈合时间 71 天)的吻合口漏均完全愈合。

结论

对于接受 LSG 的患者,非手术治疗(经皮引流、内镜、支架)是可行、安全且有效的;此外,它可能避免了全胃切除术等更具破坏性的手术。

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