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[药用糙苏根中的两种环烯醚萜苷]

[Two iridoid glycoside from roots of Phlomis medicinalis].

作者信息

Xue Hengyue, Zhang Chunhong, Wang Gangli, Lin Ruichao, Li Ping

机构信息

Dalian Institute for Drug Control, Dalian 116021, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2009 Jan;34(1):57-9.

Abstract

OBJECTIVE

To study the chemical constituents of the roots of Phlomis medicinalis.

METHOD

The compounds were isolated and repeatedly purified by macroporous resin, silica gel column chromatography, TLC and PREP-HPLC. Their structures were elucidated by physical and chemical properties and NMR spectra.

RESULT

Two iridoid glucosides were obtained and elucidated as 7-epilamalbide (1), chlorotuberoside (2).

CONCLUSION

Compound 1 was a new compound, compound 2 was isolated from the plant for the first time.

摘要

目的

研究药用糙苏根的化学成分。

方法

采用大孔树脂、硅胶柱色谱、薄层色谱和制备型高效液相色谱对化合物进行分离和反复纯化。通过理化性质和核磁共振光谱对其结构进行鉴定。

结果

得到两个环烯醚萜苷类化合物,分别鉴定为7-表拉马苷(1)、氯马铃薯苷(2)。

结论

化合物1为新化合物,化合物2首次从该植物中分离得到。

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