Xue Hengyue, Zhang Chunhong, Wang Gangli, Lin Ruichao, Li Ping
Dalian Institute for Drug Control, Dalian 116021, China.
Zhongguo Zhong Yao Za Zhi. 2009 Jan;34(1):57-9.
To study the chemical constituents of the roots of Phlomis medicinalis.
The compounds were isolated and repeatedly purified by macroporous resin, silica gel column chromatography, TLC and PREP-HPLC. Their structures were elucidated by physical and chemical properties and NMR spectra.
Two iridoid glucosides were obtained and elucidated as 7-epilamalbide (1), chlorotuberoside (2).
Compound 1 was a new compound, compound 2 was isolated from the plant for the first time.
研究药用糙苏根的化学成分。
采用大孔树脂、硅胶柱色谱、薄层色谱和制备型高效液相色谱对化合物进行分离和反复纯化。通过理化性质和核磁共振光谱对其结构进行鉴定。
得到两个环烯醚萜苷类化合物,分别鉴定为7-表拉马苷(1)、氯马铃薯苷(2)。
化合物1为新化合物,化合物2首次从该植物中分离得到。