Birch Eileen E, Wang Jingyun
Department of Ophthalmology, UT Southwestern Medical Center, Pediatric Eye Research Laboratory, Retina Foundation of the Southwest, Dallas, Texas 75231, USA.
Optom Vis Sci. 2009 Jun;86(6):647-52. doi: 10.1097/OPX.0b013e3181a6168d.
To review what is known about the normal maturation of stereoacuity, the stereoacuity deficits associated with infantile and accommodative esotropia, the rationale for making improved stereoacuity a goal of treatment, and strategies for improving stereoacuity outcomes.
Studies of stereoacuity maturation during normal development, studies of stereoacuity outcomes after treatment for infantile and accommodative esotropia, and studies of primate models of esotropia are reviewed.
Stereoacuity maturation normally proceeds rapidly during the first year of life. Infantile and accommodative esotropia are associated with profound and permanent disruption of stereopsis. Although rehabilitation of stereoacuity after treatment of esotropia remains a challenge, even the achievement of subnormal stereoacuity may have real benefits to the child.
Some abnormalities in stereoacuity may exist before the onset of esotropia, but others may result directly from abnormal binocular experience. Several strategies for improving stereoacuity outcomes in esotropia are currently under active investigation. Improved stereoacuity outcomes are associated with better long-term stability of alignment, reduced risk for and severity of amblyopia, improved achievement of sensorimotor developmental milestones, better reading ability, and improved long-term quality of life.
回顾关于立体视锐度正常发育、与婴儿型和调节性内斜视相关的立体视锐度缺陷、将改善立体视锐度作为治疗目标的基本原理以及改善立体视锐度结果的策略的已知信息。
回顾正常发育过程中立体视锐度发育的研究、婴儿型和调节性内斜视治疗后立体视锐度结果的研究以及内斜视灵长类动物模型的研究。
立体视锐度在生命的第一年通常迅速发育成熟。婴儿型和调节性内斜视与立体视觉的严重且永久性破坏有关。尽管内斜视治疗后立体视锐度的恢复仍然是一个挑战,但即使达到低于正常的立体视锐度也可能对儿童有实际益处。
一些立体视锐度异常可能在内斜视发作前就已存在,但其他异常可能直接由异常的双眼经验导致。目前正在积极研究几种改善内斜视立体视锐度结果的策略。改善的立体视锐度结果与更好的长期眼位稳定性、降低弱视的风险和严重程度、更好地实现感觉运动发育里程碑、更好的阅读能力以及改善长期生活质量相关。