Calvani M
Divisione Pediatrica, Ospedale Regionale San Camillo de Lellis, Roma.
Minerva Pediatr. 1991 Jul-Aug;43(7-8):481-92.
Acute rheumatic fever in the young: a review of historical land marks and the current status of rheumatic fever are discussed. The follows are presented here: prevent-day epidemiology; the role of group A streptococcus and the reappearance of "rheumatogenic" serotypes; the host's susceptibility and the tantalizing possibility of a genetic basis; the basis of autoimmune pathogenesis (so-called molecular mimicry); the increasing diagnostic difficulties and the critical review of Jones criteria; the reassessment of primary prevention and the couvent possibility of a streptococcal vaccine.