Lefrère J-J, Coudurier N
Département des agents Transmissibles par le Sang,Institut National de la Transfusion Sanguine, 75015 Paris, France.
Transfus Clin Biol. 2009 May;16(2):148-51. doi: 10.1016/j.tracli.2009.03.019. Epub 2009 May 12.
Donor and recipient sample biobanks are a precious tool in hemovigilance studies as well as in epidemiological and biological research, in particular with regards to safety against blood-borne agents. This paper describes the main transfusion biobanks existing in France and gives their advantages and limits. The National blood donation biobank, organized for medicolegal reasons, preserves samples of each blood donation for a 5-year period. The biobank of the Blood and Organ Transmissible Infectious Agents (BOTIA) project stocks paired donor-recipient samples with a research objective. Preserved over a long period of time, such transfusion biobanks will be useful in terms of public health, as a reflection of the biological state of a population at a given moment.
供体和受体样本生物库是血液监测研究以及流行病学和生物学研究中的宝贵工具,特别是在防范血源性病原体方面。本文介绍了法国现有的主要输血生物库,并阐述了它们的优缺点。出于法医学原因设立的国家献血生物库会保存每次献血的样本,为期5年。血液和器官可传播感染因子(BOTIA)项目的生物库存储配对的供体-受体样本,用于研究目的。这些输血生物库长期保存,从反映特定时刻人群的生物学状态来看,将对公共卫生有益。