自身免疫性和胆汁淤积性肝脏疾病的管理。

Management of autoimmune and cholestatic liver disorders.

作者信息

Krok Karen L, Munoz Santiago J

机构信息

Division of Gastroenterology and Hepatology, University of Pennsylvania School of Medicine, 3400 Spruce Street, 3 Ravdin, Philadelphia, PA 19104, USA.

出版信息

Clin Liver Dis. 2009 May;13(2):295-316. doi: 10.1016/j.cld.2009.02.011.

DOI:10.1016/j.cld.2009.02.011

PMID:19442920

Abstract

The management of autoimmune and cholestatic liver disorders is a challenging area of hepatology. Autoimmune and cholestatic liver diseases represent a comparatively small proportion of hepatobiliary disorders, yet their appropriate management is of critical importance for patient survival. In this article, management strategies are discussed, including the indications and expectations of pharmacologic therapy, endoscopic approaches, and the role of liver transplantation.

摘要

自身免疫性和胆汁淤积性肝病的管理是肝病学中一个具有挑战性的领域。自身免疫性和胆汁淤积性肝病在肝胆疾病中所占比例相对较小，但其恰当的管理对患者的生存至关重要。本文讨论了管理策略，包括药物治疗的适应证和预期效果、内镜治疗方法以及肝移植的作用。