Bonnet S, Kohneh-Shahri N, Goere D, Deshayes I, Ayadi S, Elias D
Département de chirurgie générale oncologique, institut Gustave-Roussy, 39, rue Camille-Desmoulins, 94805 Villejuif cedex, France.
J Chir (Paris). 2009 Feb;146(1):6-14. doi: 10.1016/j.jchir.2009.02.002. Epub 2009 Apr 10.
Cancerous invasion of the celiac trunk is usually considered a contraindication to attempts at curative resection. Appleby was the first to propose an en bloc resection of the celiac trunk along with the celiac nervous plexus and lymph nodes for advanced gastric cancer. We describe a "modified Appleby technique" without gastrectomy for locally advanced cancer of the body of the pancreas. It accomplishes radical tumor resection, relieves pain, and improves the quality of life and overall prognosis. The principal complications are pancreatic fistula and gastric ischemia. Preoperative embolization of the common hepatic artery helps to develop favorable collateral blood flow and to avoid ischemia of the hepatobiliary system. A stomach-preserving" Appleby resection" may be appropriate treatment for selected nonaggressive cancers of the midpancreas; preoperative embolization of the common hepatic artery is an important adjunct of this technique.
腹腔干癌性侵犯通常被视为根治性切除尝试的禁忌证。阿普尔比最早提出将腹腔干与腹腔神经丛及淋巴结整块切除用于治疗进展期胃癌。我们描述了一种针对胰腺体部局部进展期癌的“改良阿普尔比技术”,该技术无需行胃切除术。它能实现肿瘤根治性切除,缓解疼痛,提高生活质量及总体预后。主要并发症为胰瘘和胃缺血。肝总动脉术前栓塞有助于建立良好的侧支血流并避免肝胆系统缺血。保留胃的“阿普尔比切除术”可能是治疗部分非侵袭性胰体癌的合适方法;肝总动脉术前栓塞是该技术的一项重要辅助措施。