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克赖斯特彻奇一年的蓄意自我中毒情况。

A year of intentional self poisoning in Christchurch.

作者信息

Buchanan W J

机构信息

Department of Anaesthetics, Christchurch Hospital.

出版信息

N Z Med J. 1991 Nov 13;104(923):470-2.

PMID:1945173
Abstract

OBJECTS

a descriptive study to determine the pattern and resource usage of intentional self poisonings presenting to an urban emergency department.

METHODS

all intentional self poisonings presenting to the sole emergency department in Christchurch during 1989 were reviewed.

RESULTS

the 531 self poisonings represented 1% of attendances with peak demand on emergency services during the evenings. Sixty-four percent were admitted accounting for 16.5% of ICU admissions and 8.5% of acute medical admissions with a mean hospital stay of two days. Only 5% of patients suffered complications, despite the potential seriousness of many events, with an overall mortality rate of 0.5%. The self poisoning rate in Christchurch is currently 20 per 10,000 population. The most frequently involved drugs were benzodiazepines (23%), tricyclic antidepressants (16%) and paracetamol (11%). There were no barbiturate poisonings and no deaths due to tricyclic antidepressants despite their prevalence amongst admissions. All beta blocker poisonings required ICU admission and one death resulted.

CONCLUSIONS

self poisoning is an activity associated with a low morbidity and mortality that remains a resource consuming problem, even in postbarbiturate times. It is infrequently seen acutely by general practitioners however it is a condition that needs greater awareness as prescribed drugs are usually involved. The tricyclic antidepressants and the beta blockers are of relatively greater importance in utilising ICU services.

摘要

目的

进行一项描述性研究,以确定前往城市急诊科的故意自我中毒的模式和资源使用情况。

方法

对1989年期间前往克赖斯特彻奇唯一急诊科的所有故意自我中毒病例进行了回顾。

结果

531例自我中毒病例占就诊人数的1%,急诊服务需求在晚上达到高峰。64%的患者被收治,占重症监护病房(ICU)收治病例的16.5%,急性内科收治病例的8.5%,平均住院时间为两天。尽管许多中毒事件潜在严重性高,但只有5%的患者出现并发症,总体死亡率为0.5%。克赖斯特彻奇目前的自我中毒率为每10000人口20例。最常涉及的药物是苯二氮䓬类(23%)、三环类抗抑郁药(16%)和对乙酰氨基酚(11%)。没有巴比妥类药物中毒病例,尽管三环类抗抑郁药在收治病例中很常见,但没有因三环类抗抑郁药导致的死亡。所有β受体阻滞剂中毒患者均需入住ICU,并有1例死亡。

结论

自我中毒是一种发病率和死亡率较低的行为,但仍是一个消耗资源的问题,即使在巴比妥类药物时代之后也是如此。全科医生很少能急性见到这种情况,然而由于通常涉及处方药,这是一种需要提高认识的病症。三环类抗抑郁药和β受体阻滞剂在占用ICU服务方面相对更为重要。

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