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儿童开放性胫骨骨折:文献系统综述。

Open tibial fractures in the paediatric population: a systematic review of the literature.

机构信息

Centre for Sports and Exercise Medicine Barts and The London School of Medicine and Dentistry, Mile End Hospital, London, UK.

出版信息

Br Med Bull. 2009;91:75-85. doi: 10.1093/bmb/ldp019. Epub 2009 May 27.

Abstract

INTRODUCTION

Open tibial fractures have been studied extensively in adults, and detailed treatment strategies have been developed: wound irrigation and debridement, fracture stabilization and delayed primary wound closure or early flap coverage are basic principles of management. No clear guidelines regarding the management of open tibial fractures in children exist.

SOURCES OF DATA

We searched Medline, Embase, Cochrane, CINAHL and Google Scholar databases using the keywords: 'open', 'tibia', 'fracture', 'children', 'paediatric', 'pediatric', 'external fixation', 'nailing'. Fourteen clinical studies were included. Quality of the studies was assessed using the Coleman Methodology Score.

AREAS OF AGREEMENT

Age above 10 years and grade III (severe) open fractures are associated with complications and outcomes similar to those in adults.

AREAS OF CONTROVERSY

It is unclear whether open fractures of the tibia in children should be managed according to the principles followed in adults. Many authors support primary skin closure and non-operative management for grade I open fractures. There is no clear effect of fracture fixation method on time to union.

GROWING POINTS

The quality of the studies was relatively poor. Patients' age affects outcome; adolescents should probably be managed as adults.

AREAS TIMELY FOR DEVELOPING RESEARCH

Carefully designed prospective cohort studies including a large number of children would be of value. Adequate follow-up is necessary to assess the long-term effects in the growing skeleton. The efficacy of flexible intramedullary nailing for open fractures needs further evaluation. Outcome studies based on general health measures are needed.

摘要

引言

成人开放性胫骨骨折已有广泛研究,并制定了详细的治疗策略:伤口冲洗和清创、骨折固定以及延迟一期伤口闭合或早期皮瓣覆盖是治疗的基本原则。目前尚无关于儿童开放性胫骨骨折处理的明确指南。

资料来源

我们使用关键词“开放性”、“胫骨”、“骨折”、“儿童”、“儿科”、“小儿”、“外固定”、“钢钉”,在 Medline、Embase、Cochrane、CINAHL 和 Google Scholar 数据库中进行检索。共纳入 14 项临床研究。使用 Coleman 方法学评分评估研究质量。

共识领域

10 岁以上和 III 级(严重)开放性骨折与成人相似,与并发症和结局相关。

争议领域

儿童胫骨开放性骨折是否应遵循成人治疗原则存在争议。许多作者支持 I 级开放性骨折行一期皮肤闭合和非手术治疗。骨折固定方法对愈合时间无明显影响。

待发展领域

研究质量相对较差。患者年龄影响结局;青少年可能应按成人处理。

适时研究领域

包括大量儿童的精心设计的前瞻性队列研究将具有价值。需要充分随访以评估生长骨骼的长期影响。还需要进一步评估弹性髓内钉治疗开放性骨折的疗效。需要基于一般健康指标的预后研究。

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