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钕钇铝石榴石激光前房角穿刺在小梁切开术中的应用:非穿透性青光眼手术中的穿刺

Nd:YAG laser goniopuncture in viscocanalostomy: penetration in non-penetrating glaucoma surgery.

作者信息

Alp Mehmet Numan, Yarangumeli Alper, Koz Ozlem Gurbuz, Kural Gulcan

机构信息

Department of Ophthalmology, Numune Training and Research Hospital, Dr Mediha Eldem Sokak. 69/10, Kocatepe, 06640, Ankara, Turkey.

出版信息

Int Ophthalmol. 2010 Jun;30(3):245-52. doi: 10.1007/s10792-009-9312-0. Epub 2009 May 29.

Abstract

The objective was to evaluate the results of Nd:YAG laser goniopuncture after viscocanalostomy and to investigate the rate of penetration in non-penetrating surgery. Results of viscocanalostomy and incidence of goniopuncture were retrospectively investigated in 33 eyes of 33 patients. Success was defined as an intraocular pressure (IOP) below 19 mmHg with an at least 30% decrease compared to the last preoperative measurement. General success rates after a mean follow-up of 33.5 +/- 11.3 months were 79 and 46%, with and without medications, respectively. Mean IOP levels, which were 37.7 +/- 9.9 mmHg at the diagnosis without treatment and 27.7 +/- 11.3 mmHg at the last preoperative measurement with medical treatment, significantly decreased to 12.7 +/- 4.8 mmHg at the last follow-up visit (P < 0.001 for both comparisons). Twelve eyes (36%) with IOPs higher than 18 mmHg during follow-up underwent laser goniopuncture. Mean IOP, which was 26.0 +/- 4.6 mmHg before goniopuncture, decreased to 11.5 +/- 4.0 mmHg immediately after the procedure (P = 0.002). Early goniopunctures (before month 3) were performed in six eyes, and late goniopunctures (after month 10) were performed in the remaining six eyes. Success rates of laser-applied eyes at the last visit were 75 and 33%, with and without medications, respectively (P = 0.568). No significant difference was found between eyes with and without goniopunctures in terms of success rates, IOP levels, and IOP reduction rates. According to the results of this study, laser goniopuncture is indicated in a significant proportion of patients following viscocanalostomy and may substantially improve the outcome of surgery.

摘要

目的是评估粘小管切开术后钕钇铝石榴石激光前房角穿刺的结果,并研究非穿透性手术中的穿刺率。对33例患者的33只眼进行了粘小管切开术的结果及前房角穿刺发生率的回顾性研究。成功定义为眼压(IOP)低于19 mmHg,与术前最后一次测量相比至少降低30%。平均随访33.5±11.3个月后的总体成功率分别为79%(使用药物)和46%(未使用药物)。未经治疗诊断时的平均眼压水平为37.7±9.9 mmHg,术前最后一次测量使用药物治疗时为27.7±11.3 mmHg,在最后一次随访时显著降至12.7±4.8 mmHg(两次比较P均<0.001)。随访期间眼压高于18 mmHg的12只眼(36%)接受了激光前房角穿刺。穿刺前平均眼压为26.0±4.6 mmHg,穿刺后立即降至11.5±4.0 mmHg(P = 0.002)。6只眼进行了早期前房角穿刺(3个月前),其余6只眼进行了晚期前房角穿刺(10个月后)。最后一次随访时,接受激光治疗的眼的成功率分别为75%(使用药物)和33%(未使用药物)(P = 0.568)。在前房角穿刺眼和未穿刺眼之间,成功率、眼压水平和眼压降低率方面均未发现显著差异。根据本研究结果,粘小管切开术后相当一部分患者需要进行激光前房角穿刺,这可能会显著改善手术效果。

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