Nyunt Ma Shwe Zin, Fones Calvin, Niti Mathew, Ng Tze-Pin
Department of Psychological Medicine, National University of Singapore, National University Hospital, 119074 Singapore.
Aging Ment Health. 2009 May;13(3):376-82. doi: 10.1080/13607860902861027.
Few studies have evaluated the validation of 15-item Geriatric Depression Scale (GDS-15) in a heterogeneous population with different age, ethnicity and comorbidities of elderly users of social services in the community.
To assess the criterion validity and reliability of the GDS-15 and its equivalence across different gender, age groups, ethnicity and different comorbidities in community living elderly and nursing homes residents.
A validation sample of non-demented 4253 elderly (age > or = 60 years), who regularly use community based care corner, senior activity center, day care center, sheltered homes and nursing homes were interviewed using the GDS-15. Structured clinical interview (SCID) was used to make DSM-IV diagnosis of major depressive disorder (MDD).
The overall sensitivity and specificity were 0.97 and 0.95, respectively (area under curve, AUC was 0.98). The overall Cronbach's alpha was 0.80, and intraclass coefficient of test--retest reliability over 2 weeks was 0.83 and inter-rater reliability was 0.94 (intra-class) and 0.99 (Cohen's kappa). Although some items in the GDS-15 appeared to be biased by gender, age and ethnicity, there were no clinically significant differences in test performance among different age, gender, ethnicity and comorbidities at cutoff of 4/5.
The GDS-15 was a reliable and valid screening for MDD across different age, gender, ethnicity and chronic illness status in the community and social service setting.
很少有研究评估15项老年抑郁量表(GDS - 15)在社区中不同年龄、种族且患有多种合并症的社会服务老年用户这一异质性人群中的效度。
评估GDS - 15的效标效度和信度,以及其在社区居住的老年人和养老院居民中不同性别、年龄组、种族和不同合并症之间的等效性。
使用GDS - 15对4253名年龄≥60岁、非痴呆且经常使用社区护理站、老年活动中心、日间护理中心、庇护所和养老院的老年人进行访谈。采用结构化临床访谈(SCID)对重度抑郁症(MDD)进行DSM - IV诊断。
总体敏感性和特异性分别为0.97和0.95(曲线下面积,AUC为0.98)。总体Cronbach's α为0.80,2周内重测信度的组内系数为0.83,评分者间信度为0.94(组内)和0.99(Cohen's κ)。尽管GDS - 15中的一些条目似乎受性别、年龄和种族的影响,但在临界值为4/5时,不同年龄、性别、种族和合并症之间的测试性能在临床上无显著差异。
在社区和社会服务环境中,GDS - 15是一种针对不同年龄、性别、种族和慢性病状况的MDD可靠且有效的筛查工具。