孕妇中伯氏考克斯氏体和流产布鲁氏菌的血清阳性率。

Seroprevalence of Coxiella burnetii and Brucella abortus among pregnant women.

作者信息

Baud D, Peter O, Langel C, Regan L, Greub G

机构信息

Center for Research on Intracellular Bacteria, Institute of Microbiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.

出版信息

Clin Microbiol Infect. 2009 May;15(5):499-501. doi: 10.1111/j.1469-0691.2009.02779.x.

DOI:10.1111/j.1469-0691.2009.02779.x

PMID:19489927

Abstract

Coxiella burnetii and Brucella abortus are two intracellular bacteria implicated in zoonotic miscarriage. In the present study, C. burnetii and B. abortus seroprevalence was compared among women from London with and without miscarriage. Coxiella burnetii seroprevalence was high (4.6%, 95% CI 2.8-7.1) despite the rare apparent exposure of this urban population. Only two patients exhibited anti-B. abortus antibodies. As a result of the risk of chronic Q fever with endocarditis and/or hepatitis, the mode of Coxiella burnetii infection in this population merits further investigation.

摘要

伯氏考克斯氏体和流产布鲁氏菌是两种与动物源性流产有关的胞内细菌。在本研究中，对伦敦有流产史和无流产史的女性进行了伯氏考克斯氏体和流产布鲁氏菌血清阳性率的比较。尽管该城市人群明显接触机会稀少，但伯氏考克斯氏体血清阳性率仍较高（4.6%，95%可信区间2.8 - 7.1）。仅有两名患者检测出抗流产布鲁氏菌抗体。鉴于存在慢性Q热伴心内膜炎和/或肝炎的风险，该人群中伯氏考克斯氏体的感染方式值得进一步研究。