Wang Xinwei, Chen Yu, Chen Deyu, Yuan Wen, Chen Xiongsheng, Zhou Xuhui, Xiao Jianru, Ni Bin, Jia Lianshun
Department of Orthopedic Surgery, Affiliated Hospital of the Second Military Medical University of PLA, Shanghai, China.
J Spinal Disord Tech. 2009 Jun;22(4):240-5. doi: 10.1097/BSD.0b013e31816d5f7e.
A retrospective clinical study of 64 patients who underwent anterior cervical discectomy and fusion (ACDF) with BAK/C for disc degenerative disorders.
To evaluate the long-term outcome of BAK/C in the treatment of cervical disc degenerative disorders.
ACDF has been demonstrated to be effective in the treatment of cervical disc degenerative disorders. BAK/C, a kind of thread cage widely used for interbody fusion in the lumbar spine, was used in the cervical spine to avoid the donor site complications of traditional autologous bone graft.
Sixty-four patients with cervical disc degenerative disorders underwent ACDF with BAK/C technique in our institution between September 1997 and December 2000. All the patients were followed up for at least 6 years. The changes of segmental stability, bone fusion, cervical lordosis, and intervertebral height on radiographs were evaluated in detail immediately after operation, at 6 and 12 months postoperatively, and yearly thereafter. The clinical outcome of neurologic improvement and pain relief was also investigated.
Solid fusion was achieved at 1 year postoperatively in all patients, and the segmental stability was maintained during the whole follow-up. The cervical lordosis and intervertebral height were well restored immediately after operation, and gradually lost during the follow-up. Especially, the anterior height of intervertebral space decreased significantly after 1 year, when compared with the anterior height immediately after operation. BAK/C subsidence was observed in 9 patients, including 5 with 1-level fusion, 1 with 2-separated-level fusion, and 3 with 2-adjacent-level fusion, according to the standard of loss of intervertebral height more than 3 mm. BAK/C fusion was generally effective in the treatment of cervical disc degenerative disorders, according to the evaluation of neurologic improvement and pain relief. However, neck pain tended to reoccur in the patients with cage subsidence, and 2 of them even needed revision surgery because of the recurrence of myelopathy and progressive neck pain.
Although BAK/C technique was generally effective and safe in the treatment of cervical disc degenerative disorders, the pitfalls of cage design resulted in the disability of maintenance of cervical lordosis and intervertebral height in the long-term follow-up. Cage subsidence, which tended to develop in the patients with 2-level fusion, was possibly responsible for the recurrence of neck pain.
一项对64例行前路颈椎间盘切除融合术(ACDF)并使用BAK/C治疗椎间盘退变疾病患者的回顾性临床研究。
评估BAK/C治疗颈椎间盘退变疾病的长期疗效。
ACDF已被证明在治疗颈椎间盘退变疾病方面有效。BAK/C是一种广泛用于腰椎椎间融合的螺纹融合器,被用于颈椎以避免传统自体骨移植的供区并发症。
1997年9月至2000年12月期间,我院64例颈椎间盘退变疾病患者接受了BAK/C技术的ACDF手术。所有患者均随访至少6年。详细评估术后即刻、术后6个月和12个月以及此后每年的X线片上节段稳定性、骨融合、颈椎前凸和椎间高度的变化。还调查了神经功能改善和疼痛缓解的临床结果。
所有患者术后1年实现了牢固融合,整个随访期间节段稳定性得以维持。颈椎前凸和椎间高度术后即刻恢复良好,但在随访期间逐渐丢失。特别是,与术后即刻的椎间隙前缘高度相比,术后1年后椎间隙前缘高度显著降低。根据椎间高度丢失超过3mm的标准,9例患者出现BAK/C下沉,其中5例为单节段融合,1例为双节段分离融合,3例为双节段相邻融合。根据神经功能改善和疼痛缓解的评估,BAK/C融合术在治疗颈椎间盘退变疾病方面总体有效。然而,融合器下沉的患者颈部疼痛往往会复发,其中2例甚至因脊髓病复发和进行性颈部疼痛而需要翻修手术。
尽管BAK/C技术在治疗颈椎间盘退变疾病方面总体有效且安全,但融合器设计的缺陷导致在长期随访中无法维持颈椎前凸和椎间高度。融合器下沉在双节段融合患者中更容易发生,可能是颈部疼痛复发的原因。