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Mutiniside,一种来自黄花稔的新型抗氧化酚类葡糖苷。

Mutiniside, new antioxidant phenolic glucoside from Abutilon muticum.

作者信息

Ali Samar, Yasmeen Shazia, Afza Nighat, Malik Abdul, Iqbal Lubna, Lateef Mehreen, Riaz Naheed, Ashraf Muhammad

机构信息

Pharmaceutical Research Centre, PCSIR Laboratories Complex Karachi, Karachi, Pakistan.

出版信息

J Asian Nat Prod Res. 2009;11(5):457-64. doi: 10.1080/10286020902835539.

Abstract

Mutiniside (1), new phenolic glucoside, and the flavonoidal glucoside cephacoside (2) have been isolated from the n-BuOH soluble fraction, along with lupeol (3), beta-sitosterol (4), stigmasterol (5), methyl-4-hydroxybenzoate (6), taraxacin (7), ursolic acid (8), and beta-sitosterol-3-O-beta-D-glucopyranoside (9), have been isolated from the EtOAc soluble fraction of Abutilon muticum. Compounds 2-9 are reported for the first time from this species. Compound 1 showed significant antioxidant activity while moderate inhibitory activity was observed against the enzyme lipoxygenase.

摘要

从黄花稔的乙酸乙酯可溶部分中分离出了mutiniside(1)、一种新的酚类糖苷以及黄酮类糖苷cephacoside(2),同时还分离出了羽扇豆醇(3)、β-谷甾醇(4)、豆甾醇(5)、4-羟基苯甲酸甲酯(6)、蒲公英苦素(7)、熊果酸(8)以及β-谷甾醇-3-O-β-D-吡喃葡萄糖苷(9)。从黄花稔的正丁醇可溶部分中分离出了化合物2 - 9。化合物2 - 9首次从该物种中报道。化合物1表现出显著的抗氧化活性,同时对脂氧合酶具有中等抑制活性。

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