Ali Samar, Yasmeen Shazia, Afza Nighat, Malik Abdul, Iqbal Lubna, Lateef Mehreen, Riaz Naheed, Ashraf Muhammad
Pharmaceutical Research Centre, PCSIR Laboratories Complex Karachi, Karachi, Pakistan.
J Asian Nat Prod Res. 2009;11(5):457-64. doi: 10.1080/10286020902835539.
Mutiniside (1), new phenolic glucoside, and the flavonoidal glucoside cephacoside (2) have been isolated from the n-BuOH soluble fraction, along with lupeol (3), beta-sitosterol (4), stigmasterol (5), methyl-4-hydroxybenzoate (6), taraxacin (7), ursolic acid (8), and beta-sitosterol-3-O-beta-D-glucopyranoside (9), have been isolated from the EtOAc soluble fraction of Abutilon muticum. Compounds 2-9 are reported for the first time from this species. Compound 1 showed significant antioxidant activity while moderate inhibitory activity was observed against the enzyme lipoxygenase.
从黄花稔的乙酸乙酯可溶部分中分离出了mutiniside(1)、一种新的酚类糖苷以及黄酮类糖苷cephacoside(2),同时还分离出了羽扇豆醇(3)、β-谷甾醇(4)、豆甾醇(5)、4-羟基苯甲酸甲酯(6)、蒲公英苦素(7)、熊果酸(8)以及β-谷甾醇-3-O-β-D-吡喃葡萄糖苷(9)。从黄花稔的正丁醇可溶部分中分离出了化合物2 - 9。化合物2 - 9首次从该物种中报道。化合物1表现出显著的抗氧化活性,同时对脂氧合酶具有中等抑制活性。