Roos Susanne, Kärner Anita, Hallert Claes
Department of Social and Welfare Studies, Faculty of Health Sciences, Linköping University, Norrköping, Sweden.
Gastroenterol Nurs. 2009 May-Jun;32(3):196-201. doi: 10.1097/SGA.0b013e3181a85e7b.
Women with celiac disease (CD) living on a gluten-free diet (GFD) show a lower health-related quality of life and report a higher rate of gastrointestinal (GI) symptoms than men with CD. Uncertainty exists as to whether GI symptoms may explain the poorer treatment outcome of women with CD. This study was designed to explore relationships of GI symptoms and psychological well-being in men and women with long-standing CD. Patients with CD (n = 108; 59% women), aged 45-64 years, treated with a GFD for at least 8 years were evaluated by the Gastrointestinal Symptom Rating Scale and the Psychological General Well-Being index. The results show that women with a high rate of GI symptoms have no lower level of psychological well-being than corresponding men with CD and that women with CD with reduced psychological well-being have no more GI symptoms than corresponding men. Our results fail to support the notion that the reduced subjective health in CD is explained by GI symptoms. They may be secondary to perceived difficulties in managing everyday life, suggesting that launching a nurse-led follow-up may be helpful, as has been proven to be useful in other lifelong disorders.
患有乳糜泻（CD）且遵循无麸质饮食（GFD）的女性，与患有CD的男性相比，其健康相关生活质量较低，且胃肠道（GI）症状发生率较高。目前尚不确定GI症状是否可以解释CD女性较差的治疗结果。本研究旨在探讨患有长期CD的男性和女性中GI症状与心理健康之间的关系。通过胃肠道症状评定量表和心理总体幸福感指数，对年龄在45 - 64岁、接受GFD治疗至少8年的108例CD患者（59%为女性）进行了评估。结果显示，GI症状发生率高的女性，其心理健康水平并不低于患有CD的男性，而心理健康水平降低的CD女性，其GI症状并不比患有CD的男性更多。我们的结果不支持GI症状可解释CD患者主观健康状况下降这一观点。它们可能继发于日常生活管理方面的感知困难，这表明开展由护士主导的随访可能会有所帮助，正如在其他终身性疾病中已被证明是有用的那样。
