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[麻风分枝杆菌蛋白质抗原的重要性。它们在开发麻风病疫苗方面的潜在用途]

[The importance of the protein antigens of Mycobacterium leprae. Their potential use for the development of a vaccine against leprosy].

作者信息

Vega-López F, Macotela-Ruiz E

机构信息

Departamento de Ciencias Clínicas, Escuela de Higiene y Medicina Social, Londres, Inglaterra.

出版信息

Gac Med Mex. 1991 Jan-Feb;127(1):31-9.

PMID:1959737
Abstract

The purpose of this review is to describe M. leprae antigenic structures that are considered relevant for the development of a vaccine. Other biological elements presently utilized in vaccination and immune therapy against leprosy are also reviewed, and the possibility of having in the future an effective vaccine obtained at low cost through molecular biology recombinant techniques. This review also describes some epidemiological and control aspects of leprosy within the general framework of the importance of this disease.

摘要

本综述的目的是描述被认为与疫苗开发相关的麻风分枝杆菌抗原结构。还综述了目前用于麻风病疫苗接种和免疫治疗的其他生物元件,以及未来通过分子生物学重组技术获得低成本有效疫苗的可能性。本综述还在麻风病重要性的总体框架内描述了麻风病的一些流行病学和防控方面。

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