Gabrieli John D E
Department of Brain and Cognitive Sciences and Harvard-Massachusetts Institute of Technology (MIT) Division of Health Sciences and Technology and McGovern Institute for Brain Research, MIT, 43 Vassar Street, Cambridge, MA 02139, USA.
Science. 2009 Jul 17;325(5938):280-3. doi: 10.1126/science.1171999.
Reading is essential in modern societies, but many children have dyslexia, a difficulty in learning to read. Dyslexia often arises from impaired phonological awareness, the auditory analysis of spoken language that relates the sounds of language to print. Behavioral remediation, especially at a young age, is effective for many, but not all, children. Neuroimaging in children with dyslexia has revealed reduced engagement of the left temporo-parietal cortex for phonological processing of print, altered white-matter connectivity, and functional plasticity associated with effective intervention. Behavioral and brain measures identify infants and young children at risk for dyslexia, and preventive intervention is often effective. A combination of evidence-based teaching practices and cognitive neuroscience measures could prevent dyslexia from occurring in the majority of children who would otherwise develop dyslexia.
阅读在现代社会至关重要,但许多儿童患有诵读困难症,即学习阅读有困难。诵读困难症通常源于语音意识受损,语音意识是对口语进行听觉分析,将语言的声音与文字联系起来。行为矫正,尤其是在儿童年幼时进行,对许多但并非所有儿童都有效。对患有诵读困难症的儿童进行神经成像研究发现,左颞顶叶皮层在处理文字的语音方面的参与度降低,白质连接改变,以及与有效干预相关的功能可塑性。行为和大脑测量方法可以识别有诵读困难风险的婴幼儿,预防性干预通常是有效的。将循证教学实践和认知神经科学措施相结合,可以防止大多数原本会患诵读困难症的儿童出现这种情况。