Smith Earl L, Hung Li-Fang, Huang Juan
College of Optometry, University of Houston, Houston, TX 77204-2020, USA.
Vision Res. 2009 Sep;49(19):2386-92. doi: 10.1016/j.visres.2009.07.011. Epub 2009 Jul 24.
Understanding the role of peripheral defocus on central refractive development is critical because refractive errors can vary significantly with eccentricity and peripheral refractions have been implicated in the genesis of central refractive errors in humans. Two rearing strategies were used to determine whether peripheral hyperopia alters central refractive development in rhesus monkeys. In intact eyes, lens-induced relative peripheral hyperopia produced central axial myopia. Moreover, eliminating the fovea by laser photoablation did not prevent compensating myopic changes in response to optically imposed hyperopia. These results show that peripheral refractive errors can have a substantial impact on central refractive development in primates.
了解周边离焦对中央屈光发育的作用至关重要，因为屈光不正会随偏心度而显著变化，并且周边屈光不正被认为与人类中央屈光不正的发生有关。采用两种饲养策略来确定周边远视是否会改变恒河猴的中央屈光发育。在完整的眼睛中，晶状体诱导的相对周边远视会导致中央轴性近视。此外，通过激光光凝消除中央凹并不能阻止对光学性远视作出的代偿性近视变化。这些结果表明，周边屈光不正可对灵长类动物的中央屈光发育产生重大影响。
