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糖尿病性视网膜病变中的黄斑新生血管形成:病例报告及文献综述

Foveal neovascularisation in diabetic retinopathy: case report and review of literature.

作者信息

Rajagopal Jyothsna, Kamath Anuradha G, Kamath G Girish, Solanki Narpat

机构信息

Mahaveer Eye Hospital, 2, Sirur Park Road, Seshadripuram, Bangalore, 560020, India.

出版信息

Int Ophthalmol. 2010 Jun;30(3):311-4. doi: 10.1007/s10792-009-9317-8. Epub 2009 Jul 29.

Abstract

To report a rare case of unilateral foveal neovascularisation in an asymptomatic patient with 15-year history of insulin-dependent diabetes mellitus and bilateral proliferative diabetic retinopathy and diabetic macular edema. Fundus fluorescein angiography and optical coherence tomography scan confirmed the presence of foveal neovascularisation. There was complete regression of the foveal neovascularisation after pan retinal laser photocoagulation. We review the literature on foveal neovascularisation in diabetic retinopathy and propose a possible pathogenic mechanism for development of foveal neovascularisation in diabetic retinopathy and the reason for the response to pan retinal laser photocoagulation.

摘要

报告一例罕见的无症状胰岛素依赖型糖尿病患者单侧黄斑部新生血管形成病例,该患者有15年病史,伴有双侧增殖性糖尿病视网膜病变及糖尿病性黄斑水肿。眼底荧光血管造影和光学相干断层扫描证实了黄斑部新生血管形成的存在。全视网膜激光光凝术后黄斑部新生血管完全消退。我们回顾了糖尿病视网膜病变黄斑部新生血管形成的相关文献,并提出了糖尿病视网膜病变黄斑部新生血管形成的可能发病机制以及对全视网膜激光光凝反应的原因。

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