Harris R, Mitton S, Chong S, Daya H
Department of Otolaryngology, St George's Hospital, London, UK.
J Laryngol Otol. 2010 Jan;124(1):96-100. doi: 10.1017/S0022215109990636. Epub 2009 Jul 30.
The prevalence of eosinophilic oesophagitis is increasing. A Pubmed search for 'eosinophilic oesophagitis' and 'eosinophilic esophagitis' yielded 345 publications since 1976. Only seven were in otolaryngology journals.1-7 Patients typically present with dysphagia, vomiting, dyspepsia or food impaction and are therefore usually referred to a paediatric gastroenterologist; otolaryngologists are not usually involved in management. A missed diagnosis may result in oesophageal stricture.
Two patients, aged two and four years, were referred to the paediatric otolaryngology department with intermittent upper oesophageal food impaction. A paediatric gastroenterologist was involved in the investigation. Histological examination of oesophageal biopsies demonstrated changes consistent with eosinophilic oesophagitis.
Both patients were expediently diagnosed, investigated and managed.
A diagnosis of eosinophilic oesophagitis must be considered in patients presenting with food bolus impaction. Early involvement of a paediatric gastroenterology team in the diagnosis is recommended in children presenting with oesophageal symptoms, in order to avoid delayed diagnosis.
嗜酸性粒细胞性食管炎的患病率正在上升。自1976年以来,在PubMed上搜索“嗜酸性粒细胞性食管炎”和“嗜酸性食管炎”,共得到345篇出版物。其中只有7篇发表在耳鼻喉科期刊上。1-7患者通常表现为吞咽困难、呕吐、消化不良或食物嵌塞,因此通常会被转诊给儿科胃肠病学家;耳鼻喉科医生通常不参与治疗。漏诊可能导致食管狭窄。
两名年龄分别为2岁和4岁的患者因间歇性食管上段食物嵌塞被转诊至儿科耳鼻喉科。一名儿科胃肠病学家参与了调查。食管活检的组织学检查显示与嗜酸性粒细胞性食管炎一致的变化。
两名患者均得到了及时的诊断、检查和治疗。
对于出现食物团块嵌塞的患者,必须考虑嗜酸性粒细胞性食管炎的诊断。对于出现食管症状的儿童,建议儿科胃肠病学团队尽早参与诊断,以避免延迟诊断。