Huo Lei, Bi Changlong, Fang Jiasheng, Wang Yanjin, Zhang Mingyu, Chen Fenghua
Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008,China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2009 Jul;34(7):642-5.
To explore the microneurosurgical technique and prevention of postoperative complications for the fourth ventricle tumors in adults.
We retrospectively analyzed the clinical data of 68 patients with the fourth ventricle tumors between August 2005 and August 2007 in Xiangya Hospital after microsurgical operation. Tumors were excised by inferior vermis cerebellar approach or cerebellomedullary fissure approach. The extent of tumor removal should take into consideration the possible injury of brain stem respiratory center, especially tumors adherent to the brain stem. Cerebral aqueduct obstructions were removed in all patients, suspending dura on the neck muscles during closing skull to eliminate scalp hydrops.
There were 58 total tumor excisions and 10 subtotal tumor excisions. No patient died and no suboccipital hydrops took place before discharge in this study. Postoperative symptomatic hydrocephalus was found in 10 patients, but it was cured by ventricle-abdomen shunt. Hemorrhage in tumor lumen happened in 4 patients, who received second microsurgery. Drugs were given to 8 patients with intracranial pneumatocele, 10 with intracranial infection, and 18 with upper gastrointestinal hemorrhage. Five patients out of the 16 tracheotomies recovered well by mechanical ventilation.
Protecting the life center of brain stem and dredging the aqueduct outlet completely were the key to surgical success. Therapeutic effect could be improved by adept microneurosurgical techniques after operation. The prognosis of patients may be improved by preventing complications actively and combined therapy after the operation.
探讨成人第四脑室肿瘤的显微神经外科手术技术及术后并发症的防治。
回顾性分析2005年8月至2007年8月在湘雅医院行显微手术的68例第四脑室肿瘤患者的临床资料。采用小脑蚓部下入路或小脑延髓裂入路切除肿瘤。肿瘤切除范围应考虑脑干呼吸中枢可能受到的损伤,尤其是与脑干粘连的肿瘤。所有患者均解除了中脑导水管梗阻,关颅时将硬脑膜悬吊于颈部肌肉上以消除头皮积水。
全切除肿瘤58例,次全切除肿瘤10例。本研究中无患者死亡,出院前无枕下积水发生。术后10例患者出现症状性脑积水,经脑室-腹腔分流治愈。4例患者肿瘤腔内出血,接受了二次显微手术。8例颅内积气患者、10例颅内感染患者及18例上消化道出血患者给予了相应药物治疗。16例行气管切开术的患者中有5例通过机械通气恢复良好。
保护脑干生命中枢及彻底疏通导水管出口是手术成功的关键。熟练的显微神经外科手术技术可提高术后治疗效果。积极预防并发症及术后综合治疗可改善患者预后。