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比死亡更糟糕的命运?入住外科重症监护病房的创伤患者的长期结局。

A fate worse than death? Long-term outcome of trauma patients admitted to the surgical intensive care unit.

作者信息

Livingston David H, Tripp Tovah, Biggs Carina, Lavery Robert F

机构信息

Division of Trauma, Department of Surgery, UMDNJ - New Jersey Medical School, Newark, New Jersey 07103-2406, USA.

出版信息

J Trauma. 2009 Aug;67(2):341-8; discussion 348-9. doi: 10.1097/TA.0b013e3181a5cc34.

Abstract

INTRODUCTION

Trauma centers successfully save lives of severely injured patients who would have formerly died. However, survivors often have multiple complications and morbidities associated with prolonged intensive care unit (ICU) stays. Because the reintegration of patients into the society to lead an active and a productive life is the ultimate goal of trauma center care, we questioned whether our "success" may condemn these patients to a fate worse than death?

METHODS

Charts on all patients > or =18 years with ICU stay > or =10 days, discharged alive between June 1, 2002, and May 31, 2005, were reviewed. Patients with complete spinal cord injuries were excluded. Demographics, Injury Severity Score (ISS), presence of severe traumatic brain injury (TBI; Head Abbreviated Injury Scale [AIS] score = 4 or 5), presence of extremity fractures, need for operative procedures, ventilator days, complications, and discharge disposition were collected. Glasgow Outcome Scale score was calculated on discharge. Patients were contacted by phone to determine general health, work status, and using this data, Glasgow Outcome Scale score and a modified Functional Independence Measure (FIM) score were calculated.

RESULTS

Two hundred and forty-one patients met inclusion criteria. Thirty-three patients died postdischarge from the hospital and 39 were known to be alive from the electronic medical records but were unable to be contacted. Sixty-nine patients could not be tracked down and were ultimately considered as lost to follow-up. The remaining 100 patients who were successfully contacted participated in the study. Eighty-one percent were men with a mean age of 42 years, mean and median ISS of 28. Severe TBI was present in 50 (50%) patients. Mean and median follow-up was 3.3 years from discharge. At the time of follow-up, 92 (92%) patients were living at home, 5 in nursing homes, and 3 in assisted living, a shelter, or halfway house. FIM scores ranged from 6 to 12 with 55% reached a maximal FIM score of 12. One quarter of patients had FIM scores < or =10 and 10% had locomotion scores of < or =2 (very dependent). Seventy percent considered themselves to be less active. Seventy-six patients were either working or in full-time school before their trauma. Of the 24 patients not working preinjury, 12 were > or =55 years of age. At the time of follow-up, 37 patients (49%) were back to work or school. Severe TBI patients (57%, 21 of 37) were less likely to return to work when compared with 38% (12 of 38; p = 0.03) without severe TBI. There was no relationship with age, ISS, presence of any TBI, head AIS, presence of any extremity fracture, extremity AIS, or ventilator days in patients who did or did not return to work.

CONCLUSIONS

These data demonstrate that ICU survivors >3 years after severe injury have significant impairments including inability to return to work or regain previous levels of activity and that the goal of reintegrating patients back into the society is not being met. Further studies better defining the limitations and barriers to improved quality of life are necessary. Survival, although important, is no longer a sufficient outcome to measure trauma center success.

摘要

引言

创伤中心成功挽救了许多原本会死亡的重伤患者的生命。然而,幸存者往往会出现多种并发症,且因长时间入住重症监护病房(ICU)而患有多种疾病。由于将患者重新融入社会以过上积极且有意义的生活是创伤中心护理的最终目标,我们不禁要问,我们的“成功”是否会使这些患者面临比死亡更糟糕的命运?

方法

回顾了2002年6月1日至2005年5月31日期间所有年龄≥18岁、入住ICU≥10天且存活出院的患者的病历。排除完全性脊髓损伤患者。收集了人口统计学资料、损伤严重程度评分(ISS)、严重创伤性脑损伤(TBI;头部简明损伤量表[AIS]评分为4或5)的情况、四肢骨折情况、手术需求、呼吸机使用天数、并发症及出院处置情况。出院时计算格拉斯哥预后量表评分。通过电话联系患者以确定其总体健康状况、工作状态,并据此计算格拉斯哥预后量表评分和改良的功能独立性测量(FIM)评分。

结果

241例患者符合纳入标准。33例患者出院后死亡,39例从电子病历中得知仍存活但无法联系到。69例患者无法找到,最终被视为失访。其余100例成功联系到的患者参与了研究。81%为男性,平均年龄42岁,平均ISS和中位数ISS均为28。50例(50%)患者存在严重TBI。出院后平均随访时间和中位数随访时间为3.3年。随访时,92例(92%)患者在家中生活,5例在养老院,3例在辅助生活设施、庇护所或中途之家。FIM评分范围为6至12分,55%的患者达到最大FIM评分12分。四分之一的患者FIM评分≤10分,10%的患者运动评分≤2分(非常依赖)。70%的患者认为自己活动量减少。76例患者在受伤前有工作或在全日制学校就读。在受伤前未工作的24例患者中,12例年龄≥55岁。随访时,37例患者(49%)恢复工作或上学。与无严重TBI的患者相比,严重TBI患者恢复工作(分别为57%,37例中的21例和38%,38例中的12例;p = 0.03)的可能性较小。恢复工作的患者与未恢复工作的患者在年龄、ISS、是否存在任何TBI、头部AIS、是否存在任何四肢骨折、四肢AIS或呼吸机使用天数方面均无关联。

结论

这些数据表明,重伤后3年以上的ICU幸存者存在显著损伤,包括无法恢复工作或恢复到以前的活动水平,且患者重新融入社会的目标未实现。有必要进行进一步研究,以更好地界定改善生活质量的限制因素和障碍。生存虽然重要,但已不再是衡量创伤中心成功的充分指标。

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