Younger John F, Plein Sven, Crean Andrew, Ball Stephen G, Greenwood John P
Academic Unit of Cardiovascular Medicine, University of Leeds, Leeds, UK.
J Cardiovasc Magn Reson. 2009 Aug 11;11(1):26. doi: 10.1186/1532-429X-11-26.
Coronary venous imaging with whole-heart cardiovascular magnetic resonance (CMR) angiography has recently been described using developmental pulse sequences and intravascular contrast agents. However, the practical utility of coronary venous imaging will be for patients with heart failure in whom cardiac resynchronisation therapy (CRT) is being considered. As such complementary information on ventricular function and myocardial viability will be required. The aim of this study was to determine if the coronary venous anatomy could be depicted as part of a comprehensive CMR protocol and using a standard extracellular contrast agent.
Thirty-one 3D whole heart CMR studies, performed after intravenous administration of 0.05 mmol/kg gadolinium DTPA, were reviewed. The cardiac venous system was visualized in all patients. The lateral vein of the left ventricle was present in 74%, the anterior interventricular vein in 65%, and the posterior interventricular vein in 74% of patients. The mean maximum distance of demonstrable cardiac vein on the 3D images was 81.5 mm and was dependent on the quality of the 3D data set. Five patients showed evidence of myocardial infarction on late gadolinium enhancement (LGE) images.
Coronary venous anatomy can be reliably demonstrated using a comprehensive CMR protocol and a standard extracellular contrast agent. The combination of coronary venous imaging, assessment of ventricular function and LGE may be useful in the management of patients with LV dysfunction being considered for CRT.
近期已报道了使用改进的脉冲序列和血管内造影剂,通过全心脏心血管磁共振(CMR)血管造影进行冠状静脉成像。然而,冠状静脉成像的实际用途将体现在考虑进行心脏再同步治疗(CRT)的心力衰竭患者中。因此,将需要关于心室功能和心肌存活的补充信息。本研究的目的是确定冠状静脉解剖结构能否作为综合CMR检查方案的一部分,使用标准细胞外造影剂进行描绘。
回顾了31例在静脉注射0.05 mmol/kg钆喷酸葡胺后进行的三维全心脏CMR研究。所有患者的心脏静脉系统均清晰可见。左心室侧静脉在74%的患者中存在,前室间静脉在65%的患者中存在,后室间静脉在74%的患者中存在。三维图像上可显示的心脏静脉的平均最大距离为81.5 mm,且取决于三维数据集的质量。5例患者在延迟钆增强(LGE)图像上显示有心肌梗死的证据。
使用综合CMR检查方案和标准细胞外造影剂能够可靠地显示冠状静脉解剖结构。冠状静脉成像、心室功能评估和LGE的联合应用可能有助于对考虑进行CRT的左心室功能不全患者的管理。