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[院外心脏骤停复苏患者复苏后医院间的预后差异]

[Differences between hospitals in prognosis after resuscitated out-of-hospital cardiac arrest patients].

作者信息

Kjaergaard Jesper, Bro-Jeppesen John, Rasmussen Lars Simon, Nielsen Søren Loumann, Folke Fredrik, Lippert Freddy, Wanscher Michael C, Hassager Christian

机构信息

Kardiologisk Klinik B 2142, Hjertecentret, Rigshospitalet, DK-2100 København Ø.

出版信息

Ugeskr Laeger. 2009 Jun 22;171(26):2169-73.

Abstract

INTRODUCTION

There are substantial differences in long-term survival of patients resuscitated from out-of-hospital cardiac arrest, and the level of care during hospitalization may be a contributing factor. The purpose of this study was to determine if a difference in long-term prognosis between hospitals could be detected in patients surviving cardiac arrest in Copenhagen.

MATERIAL AND METHODS

The mobile emergency care unit attempted resuscitation in 1,098 patients with out-of-hospital cardiac arrest in the period 2002 to 2006, among whom return of spontaneous circulation occurred in 336 (30%) of the patients admitted to hospital. Survival was determined using the Central Population Registry through Statistics Denmark.

RESULTS

Patients admitted to a tertiary facility were younger, more frequently male, they had more commonly ventricular fibrillation/pulseless ventricular tachycardia (VF/pVT) as their initial rhythm, and they had more frequently received bystander cardiopulmonary resuscitation. Survival at 4.6 years was 41% in patients admitted to the tertiary hospital and 10% in patients admitted to other hospitals, p < 0.0001. After adjustment for other known risk factors, patients admitted to other hospitals had a hazard ratio of 1.8 for death (95% confidence interval: 1,4-2,5) compared with patients admitted to a tertiary facility.

CONCLUSION

The survival rate after out-of-hospital cardiac arrest was significantly higher in patients admitted to a tertiary facility than among patients admitted to less specialized hospitals. Further studies are needed to identify causal factors.

摘要

引言

院外心脏骤停复苏患者的长期生存率存在显著差异,住院期间的护理水平可能是一个促成因素。本研究的目的是确定在哥本哈根心脏骤停存活患者中,能否检测到不同医院之间长期预后的差异。

材料与方法

移动急救单元在2002年至2006年期间对1098例院外心脏骤停患者进行了复苏尝试,其中336例(30%)入院患者恢复了自主循环。通过丹麦统计局的中央人口登记处确定生存率。

结果

入住三级医疗机构的患者更年轻,男性比例更高,他们更常以心室颤动/无脉性室性心动过速(VF/pVT)作为初始心律,并且更常接受旁观者心肺复苏。三级医院入院患者4.6年的生存率为41%,其他医院入院患者为10%,p<0.0001。在对其他已知风险因素进行调整后,与入住三级医疗机构的患者相比,入住其他医院的患者死亡风险比为1.8(95%置信区间:1.4-2.5)。

结论

入住三级医疗机构的院外心脏骤停患者的生存率显著高于入住专科程度较低医院的患者。需要进一步研究以确定因果因素。

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