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通过细针穿刺细胞学诊断的软骨样汗腺腺瘤。

Chondroid syringoma diagnosed by fine needle aspiration cytology.

作者信息

Kumar Bipin

机构信息

Department of Pathology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.

出版信息

Diagn Cytopathol. 2010 Jan;38(1):38-40. doi: 10.1002/dc.21159.

Abstract

Chondroid syringoma is a rare benign skin adnexal tumor of eccrine/apocrine origin affecting commonly the head and neck region. It used to be previously called as mixed tumor of skin because of the presence of both the epithelial and mesenchymal components. There are only few case reports describing the fine needle aspiration cytologic features of chondroid syringoma for diagnosis. We studied a 20-year-old male case from Taplejung district of Nepal came to Otorhinolaryngology out patient department with the complaints of painless, progressively enlarging swelling on the dorsum of nose. On examination, 2.0 x 2.0 cm, firm, non-tender swelling was seen on the right side of dorsum of nose. Overlying skin was normal, and the swelling was fixed to the skin but freely mobile over underlying structure. A clinical diagnosis of dermoid cyst was entertained, and the case was subjected to FNAC. FNA yielded mucoid material which on microscopy showed clusters of round cells with moderate to abundant cytoplasm embedded in chondromyxoid ground substance. The nuclei were monomorphic, centrally to eccentrically located and had fine chromatin. On the basis of these cytologic features, a diagnosis of chondroid syringoma was made. We concluded that Chondroid syringoma may be considered as a rare differential diagnosis in the swelling of head and neck region and the diagnosis can be easily confirmed or ruled out by means of fine needle aspiration cytology.

摘要

软骨样汗腺腺瘤是一种罕见的良性皮肤附属器肿瘤,起源于小汗腺/大汗腺,常见于头颈部区域。由于其同时存在上皮和间叶成分,过去曾被称为皮肤混合瘤。仅有少数病例报告描述了软骨样汗腺腺瘤的细针穿刺细胞学特征用于诊断。我们研究了一名来自尼泊尔塔普勒琼县的20岁男性病例,该患者因鼻背部无痛性、进行性增大的肿胀来到耳鼻喉科门诊。检查发现,鼻背部右侧有一个2.0×2.0厘米、质地坚硬、无压痛的肿胀物。其上覆盖的皮肤正常,肿胀物与皮肤粘连,但在其下方结构上可自由移动。初步考虑为皮样囊肿,并对该病例进行了细针穿刺抽吸活检(FNAC)。FNAC抽出了黏液样物质,显微镜检查显示有成群的圆形细胞,胞质中度至丰富,嵌入软骨黏液样基质中。细胞核形态单一,位于中央至偏心位置,染色质细腻。基于这些细胞学特征,诊断为软骨样汗腺腺瘤。我们得出结论,软骨样汗腺腺瘤可被视为头颈部肿胀的一种罕见鉴别诊断,通过细针穿刺细胞学检查可轻松确诊或排除。

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