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在假性剥脱性眼病的对眼中行联合超声乳化小梁吸除术后的个体内比较。

Intra-individual comparison after combined phaco-trabecular aspiration in pairs of pseudoexfoliative eyes.

机构信息

Department of Ophthalmology, University of Cologne, Joseph-Stelzmann-Str. 9, 50931 Köln, Germany.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2010 Jan;248(1):79-83. doi: 10.1007/s00417-009-1174-7. Epub 2009 Aug 21.

Abstract

BACKGROUND

Trabecular aspiration is used for combined glaucoma-cataract surgery in coexisting pseudoexfoliation syndrome (XFS) or glaucoma (XFG). Reports on this technique are limited to a few small-scale studies. In this study, we wanted to elucidate whether the result of combined phacoemulsification with trabecular aspiration in the first operated eye is predictive for outcome in the contralateral eye.

METHODS

In a retrospective analysis we compared the results from 80 eyes of 40 patients with pseudoexfoliation syndrome or glaucoma, who had undergone bilateral but consecutive phacoemulsification with implantation of a posterior chamber lens combined with trabecular aspiration between 2003 and 2005.

RESULTS

The IOP level and medication score after phaco-trabecular aspiration were shown to be significantly lower than the preoperative values after 2 years (p < 0.0001 and p = 0.047). A significant correlation between the first and second eye was detected for reduction of IOP and medication score after 1 year. Kaplan-Meier graphs of the first and second eyes showed an almost parallel trend from 1 day after surgery until 35 months after surgery.

CONCLUSIONS

The postoperative outcome in an eye after combined phaco-trabecular aspiration is predictive for the second eye. If this procedure succeeded in the first eye, the prognosis for the same strategy in the fellow eye is also good.

摘要

背景

在共存的假性剥脱综合征(XFS)或青光眼(XFG)中,小梁抽吸术用于联合青光眼白内障手术。关于该技术的报告仅限于少数小规模研究。在这项研究中,我们想阐明第一只接受手术的眼睛中联合超声乳化抽吸术的结果是否可以预测对侧眼睛的结果。

方法

我们进行了回顾性分析,比较了 2003 年至 2005 年间连续双侧接受超声乳化抽吸术联合小梁抽吸术和后房人工晶状体植入术的 40 例 XFS 或青光眼患者的 80 只眼的结果。

结果

术后 2 年,超声乳化抽吸术后的眼压水平和药物评分明显低于术前值(p < 0.0001 和 p = 0.047)。术后 1 年,第一只眼和第二只眼的眼压和药物评分之间存在显著相关性。第一只眼和第二只眼的 Kaplan-Meier 图显示,从术后 1 天到术后 35 个月,其趋势几乎平行。

结论

联合超声乳化抽吸术后一只眼的术后结果可预测第二只眼。如果该程序在第一只眼成功,那么在对侧眼采用相同策略的预后也很好。

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