pCTX-M360 是一株从中国分离的多重耐药肺炎克雷伯菌中的 pEL60 和 pCTX-M3 之间的中间质粒，其完整核苷酸序列。
Complete nucleotide sequence of pCTX-M360, an intermediate plasmid between pEL60 and pCTX-M3, from a multidrug-resistant Klebsiella pneumoniae strain isolated in China.
机构信息
State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
出版信息
Antimicrob Agents Chemother. 2009 Dec;53(12):5291-3. doi: 10.1128/AAC.00032-09. Epub 2009 Sep 14.
Abstract
In this work we report the characterization of plasmid pCTX-M360, isolated from a Klebsiella pneumoniae strain from China and encoding the CTX-M-3 extended-spectrum beta-lactamase. Sequence analysis of pCTX-M360 revealed extensive similarity with pEL60 and pCTX-M3, two other enterobacterial plasmids of the IncL/M incompatibility group. Compared to pEL60, pCTX-M360 contains several insertions but lacks most of a 27-kb insert found in pCTX-M3, suggesting that it could be an evolutionary intermediate between pEL60 and pCTX-M3.
摘要
在这项工作中，我们报告了质粒 pCTX-M360 的特征，该质粒分离自一株来自中国的肺炎克雷伯菌，编码 CTX-M-3 型超广谱β-内酰胺酶。对 pCTX-M360 的序列分析表明，它与 pEL60 和 pCTX-M3 具有高度相似性，后两者是 IncL/M 不相容群的两种其他肠杆菌质粒。与 pEL60 相比，pCTX-M360 含有几个插入片段，但缺失了 pCTX-M3 中发现的 27kb 插入片段的大部分，这表明它可能是 pEL60 和 pCTX-M3 之间的进化中间体。
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本文引用的文献
1
Prevalence and genetic characterization of blaCTX-M among Klebsiella pneumoniae isolates collected in an intensive care unit in Brazil.
J Chemother. 2008 Oct;20(5):600-3. doi: 10.1179/joc.2008.20.5.600.
2
Dominance of blaCTX-M within an Australian extended-spectrum beta-lactamase gene pool.
Antimicrob Agents Chemother. 2008 Nov;52(11):4198-202. doi: 10.1128/AAC.00107-08. Epub 2008 Aug 25.
3
The spread of CTX-M-type extended-spectrum beta-lactamases.
Clin Microbiol Infect. 2008 Jan;14 Suppl 1:33-41. doi: 10.1111/j.1469-0691.2007.01867.x.
4
The continuing challenge of ESBLs.
Curr Opin Pharmacol. 2007 Oct;7(5):459-69. doi: 10.1016/j.coph.2007.08.003. Epub 2007 Sep 17.
5
Comparative analysis of IncHI2 plasmids carrying blaCTX-M-2 or blaCTX-M-9 from Escherichia coli and Salmonella enterica strains isolated from poultry and humans.
Antimicrob Agents Chemother. 2007 Nov;51(11):4177-80. doi: 10.1128/AAC.00603-07. Epub 2007 Aug 13.
6
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Antimicrob Agents Chemother. 2007 Nov;51(11):3789-95. doi: 10.1128/AAC.00457-07. Epub 2007 Aug 13.
7
CTX-M: changing the face of ESBLs in Europe.
J Antimicrob Chemother. 2007 Feb;59(2):165-74. doi: 10.1093/jac/dkl483. Epub 2006 Dec 6.
8
Emergence and dissemination of Enterobacteriaceae isolates producing CTX-M-1-like enzymes in Spain are associated with IncFII (CTX-M-15) and broad-host-range (CTX-M-1, -3, and -32) plasmids.
Antimicrob Agents Chemother. 2007 Feb;51(2):796-9. doi: 10.1128/AAC.01070-06. Epub 2006 Dec 4.
9
Functional analysis of replication and stability regions of broad-host-range conjugative plasmid CTX-M3 from the IncL/M incompatibility group.
Plasmid. 2007 Mar;57(2):95-107. doi: 10.1016/j.plasmid.2006.09.001. Epub 2006 Nov 7.
10
Nucleotide sequences, genetic organization, and distribution of pEU30 and pEL60 from Erwinia amylovora.
Appl Environ Microbiol. 2004 Dec;70(12):7539-44. doi: 10.1128/AEM.70.12.7539-7544.2004.
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