硬化蛋白与骨卸载 - Suppr

Sclerostin and the unloading of bone.

作者信息

Suva Larry J

机构信息

Department of Orthopaedic Surgery, Center for Orthopaedic Research, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Mail Slot 644, Little Rock, AR 72205, USA.

出版信息

J Bone Miner Res. 2009 Oct;24(10):1649-50. doi: 10.1359/jbmr.090815.

DOI:10.1359/jbmr.090815

PMID:19757998

Abstract

摘要

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Sclerostin and the unloading of bone.

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Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling.

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相似文献

Sclerostin and the unloading of bone.

J Bone Miner Res. 2009 Oct;24(10):1649-50. doi: 10.1359/jbmr.090815.

Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling.

J Bone Miner Res. 2009 Oct;24(10):1651-61. doi: 10.1359/jbmr.090411.

NMR structure of the Wnt modulator protein Sclerostin.

Biochem Biophys Res Commun. 2009 Feb 27;380(1):160-5. doi: 10.1016/j.bbrc.2009.01.062. Epub 2009 Jan 21.

Paradoxical Sost gene expression response to mechanical unloading in metaphyseal bone.

Bone. 2013 Apr;53(2):515-9. doi: 10.1016/j.bone.2013.01.018. Epub 2013 Jan 19.

Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation.

J Bone Miner Res. 2007 Jan;22(1):19-28. doi: 10.1359/jbmr.061002.

Sclerostin and Wnt signaling--the pathway to bone strength.

J Clin Endocrinol Metab. 2005 Dec;90(12):6741-3. doi: 10.1210/jc.2005-2370.

Identification of the disease-causing gene in sclerosteosis--discovery of a novel bone anabolic target?

J Musculoskelet Neuronal Interact. 2004 Jun;4(2):139-42.

Harnessing the parathyroid hormone, Wnt, and bone morphogenetic protein signaling cascades for successful bone tissue engineering.

Tissue Eng Part B Rev. 2011 Dec;17(6):475-9. doi: 10.1089/ten.TEB.2011.0265. Epub 2011 Oct 6.

Sclerostin: a gem from the genome leads to bone-building antibodies.

J Bone Miner Res. 2010 Sep;25(9):1897-904. doi: 10.1002/jbmr.161.

New insights into the location and form of sclerostin.

Biochem Biophys Res Commun. 2014 Apr 18;446(4):1108-13. doi: 10.1016/j.bbrc.2014.03.079. Epub 2014 Mar 22.

引用本文的文献

Bone Cells Dynamics during Peri-Implantitis: a Theoretical Analysis.

J Oral Maxillofac Res. 2016 Sep 9;7(3):e6. doi: 10.5037/jomr.2016.7306. eCollection 2016 Jul-Sep.

The best of both worlds - managing the cancer, saving the bone.

Nat Rev Endocrinol. 2016 Jan;12(1):29-42. doi: 10.1038/nrendo.2015.185. Epub 2015 Oct 27.

The effect of single extremity-vibration on the serum sclerostin level.

J Phys Ther Sci. 2015 Jul;27(7):2105-7. doi: 10.1589/jpts.27.2105. Epub 2015 Jul 22.

Transient Effect of 17β-estradiol on Osteoporosis in Ovariectomized Rats Accompanied with Unilateral Disuse in the Early Phase.

Int J Med Sci. 2015 May 23;12(5):423-31. doi: 10.7150/ijms.11887. eCollection 2015.

Sclerostin serum levels in prostate cancer patients and their relationship with sex steroids.

Osteoporos Int. 2014 Feb;25(2):645-51. doi: 10.1007/s00198-013-2462-y. Epub 2013 Aug 1.

Sclerostin and the unloading of bone.

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