新生儿缺氧缺血性脑病的低温治疗（胎龄大于等于 36 周）。
Hypothermia for hypoxic ischemic encephalopathy in infants > or =36 weeks.
机构信息
Pregnancy and Perinatology Branch, Center for Developmental Biology and Perinatal Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
出版信息
Early Hum Dev. 2009 Oct;85(10 Suppl):S49-52. doi: 10.1016/j.earlhumdev.2009.08.015. Epub 2009 Sep 17.
Abstract
Hypoxic ischemic encephalopathy is a serious condition affecting infants which can result in death and disability. This is a summary of pathogenesis of HIE, animal studies of cooling for hypoxic and ischemic models, human hypothermia trials, and the American Academy of Pediatrics publication on hypothermia for HIE. Hypothermia for neonatal HIE is continuing to evolve as a therapy. Studies, gaps in knowledge and opportunities for research are presented herein.
摘要
缺氧缺血性脑病是一种严重影响婴儿的疾病，可导致死亡和残疾。本文总结了 HIE 的发病机制、缺氧缺血模型的动物冷却研究、人类低温试验以及美国儿科学会关于 HIE 低温治疗的出版物。新生儿 HIE 的低温治疗作为一种治疗方法仍在不断发展。本文介绍了相关研究、知识空白和研究机会。
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