反复体外受精失败女性的子宫蠕动：溴化东莨菪碱的可能治疗作用
Uterine peristalsis in women with repeated IVF failures: possible therapeutic effect of hyoscine bromide.
作者信息
Kido Aki, Togashi Kaori, Hatayama Hiroshi, Nakayama Takahiro, Yamamoto Akira, Kataoka Masako, Tulandi Togas
机构信息
Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University, Kyoto City, Kyoto, Japan.
Adachi Hospital, Kyoto, Kyoto, Japan.
出版信息
J Obstet Gynaecol Can. 2009 Aug;31(8):732-735. doi: 10.1016/S1701-2163(16)34278-5.
BACKGROUND
Uterine peristalsis, which is influenced by hormonal and cholinergic effects, may have a role in successful implantation and continuing pregnancy.
CASES
We encountered abnormal uterine peristalsis in three women who had had repeated in vitro fertilization (IVF) treatment failures. They subsequently had successful pregnancies when hyoscine bromide was administered at the time of embryo transfer.
CONCLUSION
It is possible that decreasing uterine peristalsis with use of an anticholinergic agent during IVF treatment facilitates retention of embryos and increases the probability of successful pregnancy.
背景
子宫蠕动受激素和胆碱能作用影响，可能在成功着床和持续妊娠中发挥作用。
病例
我们在三名反复体外受精（IVF）治疗失败的女性中遇到了子宫蠕动异常。她们随后在胚胎移植时使用氢溴酸东莨菪碱后成功怀孕。
结论
在IVF治疗期间使用抗胆碱能药物降低子宫蠕动，有可能促进胚胎着床并增加成功妊娠的概率。
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