Trivedi Ranak B, Blumenthal James A, O'Connor Christopher, Adams Kirkwood, Hinderliter Alan, Dupree Carla, Johnson Kristy, Sherwood Andrew
Department of Medicine, Duke University Medical Center, Durham, NC 27705, USA.
J Psychosom Res. 2009 Oct;67(4):339-46. doi: 10.1016/j.jpsychores.2009.05.014.
Elevated depressive symptoms have been linked to poorer prognosis in heart failure (HF) patients. Our objective was to identify coping styles associated with depressive symptoms in HF patients.
A total of 222 stable HF patients (32.75% female, 45.4% non-Hispanic black) completed multiple questionnaires. Beck Depression Inventory (BDI) assessed depressive symptoms, Life Orientation Test (LOT-R) assessed optimism, ENRICHD Social Support Inventory (ESSI) and Perceived Social Support Scale (PSSS) assessed social support, and COPE assessed coping styles. Linear regression analyses were employed to assess the association of coping styles with continuous BDI scores. Logistic regression analyses were performed using BDI scores dichotomized into BDI<10 vs. BDI> or =10, to identify coping styles accompanying clinically significant depressive symptoms.
In linear regression models, higher BDI scores were associated with lower scores on the acceptance (beta=-.14), humor (beta=-.15), planning (beta=-.15), and emotional support (beta=-.14) subscales of the COPE, and higher scores on the behavioral disengagement (beta=.41), denial (beta=.33), venting (beta=.25), and mental disengagement (beta=.22) subscales. Higher PSSS and ESSI scores were associated with lower BDI scores (beta=-.32 and -.25, respectively). Higher LOT-R scores were associated with higher BDI scores (beta=.39, P<.001). In logistical regression models, BDI> or =10 was associated with greater likelihood of behavioral disengagement (OR=1.3), denial (OR=1.2), mental disengagement (OR=1.3), venting (OR=1.2), and pessimism (OR=1.2), and lower perceived social support measured by PSSS (OR=.92) and ESSI (OR=.92).
Depressive symptoms in HF patients are associated with avoidant coping, lower perceived social support, and pessimism. Results raise the possibility that interventions designed to improve coping may reduce depressive symptoms.
抑郁症状加重与心力衰竭(HF)患者预后较差相关。我们的目的是确定与HF患者抑郁症状相关的应对方式。
共有222例病情稳定的HF患者(女性占32.75%,非西班牙裔黑人占45.4%)完成了多项问卷调查。贝克抑郁量表(BDI)评估抑郁症状,生活取向测验(LOT-R)评估乐观程度,ENRICHD社会支持量表(ESSI)和领悟社会支持量表(PSSS)评估社会支持,应对方式问卷(COPE)评估应对方式。采用线性回归分析评估应对方式与连续BDI得分之间的关联。使用BDI得分二分法(BDI<10与BDI>或=10)进行逻辑回归分析,以确定伴有具有临床意义的抑郁症状的应对方式。
在线性回归模型中,较高的BDI得分与COPE量表中接受(β=-0.14)、幽默(β=-0.15)、计划(β=-0.15)和情感支持(β=-0.14)子量表得分较低相关,与行为脱离(β=0.41)、否认(β=0.33)、发泄(β=0.25)和精神脱离(β=0.22)子量表得分较高相关。较高的PSSS和ESSI得分与较低的BDI得分相关(分别为β=-0.32和-0.25)。较高的LOT-R得分与较高的BDI得分相关(β=0.39,P<0.001)。在逻辑回归模型中,BDI>或=10与行为脱离(OR=1.3)、否认(OR=1.2)、精神脱离(OR=1.3)、发泄(OR=1.2)和悲观(OR=1.2)的可能性增加相关,以及与PSSS(OR=0.92)和ESSI(OR=0.92)测量的较低领悟社会支持相关。
HF患者的抑郁症状与回避应对、较低的领悟社会支持和悲观情绪相关。结果提示旨在改善应对方式的干预措施可能会减轻抑郁症状。