蛋白水解在新月柄杆菌细胞周期和发育中的作用。
The role of proteolysis in the Caulobacter crescentus cell cycle and development.
机构信息
Biozentrum of the University of Basel, Klingelbergstrasse 50/70, CH-4056 Basel, Switzerland.
出版信息
Res Microbiol. 2009 Nov;160(9):687-95. doi: 10.1016/j.resmic.2009.09.006. Epub 2009 Sep 22.
Caulobacter crescentus cell cycle progression is implemented by oscillating global transcriptional regulators that establish temporal and spatial control of modular genetic subsystems during the cell cycle. The hierarchy of this regulatory circuit is established through a combination of gene expression control and regulated proteolysis. Recent results highlight the importance of spatial organization for controlled proteolysis in C. crescentus.
新月柄杆菌的细胞周期进程是通过振荡的全局转录调控因子来实现的，这些调控因子在细胞周期中建立了模块化遗传子系统的时间和空间控制。这个调控回路的层次结构是通过基因表达控制和受调控的蛋白水解的组合来建立的。最近的结果强调了空间组织对于新月柄杆菌中受控蛋白水解的重要性。
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