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肝移植后代谢综合征及其各组分:发生率、患病率、危险因素及意义。

Metabolic syndrome and its components after liver transplantation: incidence, prevalence, risk factors, and implications.

机构信息

Food Science Post-Graduation Program, Pharmacy School, Alfa Institute of Gastroenterology, School of Medicine, Federal University of Minas Gerais, Brazil.

出版信息

Clin Nutr. 2010 Apr;29(2):175-9. doi: 10.1016/j.clnu.2009.08.008. Epub 2009 Sep 23.

Abstract

Metabolic syndrome is defined as the mutual existence of obesity, impaired fasting glucose levels, insulin resistance, hypertension, and dyslipidemia. After liver transplantation, patients typically develop these disorders, and even though there has been minimal research focused on the chronic impact of this syndrome on post-liver transplant patients, studies point to an association with major vascular events and fibrosis. The aim of the current work is to review data on the incidence, prevalence, risk factors, and implications of metabolic syndrome and its components in patients who have undergone liver transplantation.

摘要

代谢综合征的定义为肥胖、空腹血糖受损、胰岛素抵抗、高血压和血脂异常同时存在。肝移植术后患者通常会出现这些疾病,虽然针对该综合征对肝移植术后患者的慢性影响的研究较少,但研究表明其与重大血管事件和纤维化相关。本研究旨在综述肝移植术后患者代谢综合征及其各组分的发生率、患病率、危险因素和影响相关数据。

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