Faculty of Medicine, Department of Medicine (C5121), University of Manitoba, 409 Tache Avenue, Winnipeg, Manitoba, R2H 2A6, Canada.
Osteoporos Int. 2010 Aug;21(8):1317-22. doi: 10.1007/s00198-009-1080-1. Epub 2009 Oct 3.
We identified hospitalizations throughout Canada during 2000-2005 in which the most responsible diagnosis was a proximal femoral fracture. Use of the US fracture risk assessment tool (FRAX) would be inappropriate for Canada as it would overestimate fracture risk in Canadian women and older men.
It is recommended that the WHO fracture risk assessment tool should be calibrated to the target population.
We identified hospitalizations for women and men throughout Canada during the study period 2000-2005 in which the most responsible diagnosis was a proximal femoral fracture (147,982 hip fractures). Age-standardized hip fracture rates were compared between Canadian provinces, and national rates were compared with those reported for the USA and Germany.
There were relatively small differences in hip fracture rates between provinces, and most did not differ appreciably from the Canadian average. Hip fracture rates for women in Canada in 2001 were substantially lower than in the USA (population-weighted rate ratio 0.70) and were also lower than in Germany for 2004 (population-weighted rate ratio 0.74).
Overall hip fracture rates for Canadian women were found to be substantially lower than those for the USA and Germany. This study underscores the importance of assessing country-specific fracture patterns prior to adopting an existing FRAX tool.
我们在 2000-2005 年期间确定了加拿大各地因最主要诊断为股骨近端骨折而住院的病例。由于美国骨折风险评估工具(FRAX)会高估加拿大女性和老年男性的骨折风险,因此不适合在加拿大使用。
建议对世界卫生组织骨折风险评估工具进行校准,以适应该工具的目标人群。
我们在 2000-2005 年期间确定了加拿大各地因最主要诊断为股骨近端骨折(147982 例髋部骨折)而住院的病例。比较了加拿大各省之间的年龄标准化髋部骨折发生率,并将全国发生率与美国和德国的报告发生率进行了比较。
各省之间的髋部骨折发生率差异相对较小,大多数与加拿大的平均水平没有明显差异。加拿大 2001 年女性髋部骨折发生率明显低于美国(人口加权率比 0.70),也低于 2004 年德国的髋部骨折发生率(人口加权率比 0.74)。
加拿大女性的总体髋部骨折发生率明显低于美国和德国。本研究强调了在采用现有的 FRAX 工具之前,评估特定国家的骨折模式的重要性。