Department of Paediatric Nephrology, University Medical Centre, Ljubljana, Slovenia.
Acta Paediatr. 2010 Mar;99(3):470-3. doi: 10.1111/j.1651-2227.2009.01531.x. Epub 2009 Oct 5.
Urinary tract infections, renal abscess formation and acute renal failure (ARF) after salmonella infection are rarely reported in children. We present a previously healthy teenager who developed ARF with renal abscess formation after salmonella infection, in whom we believe that acute salmonella pyelonephritis was the main causative factor for ARF and not dehydration, shock or rhabdomyolysis, which have already been described in the literature. With prolonged antibiotic treatment and adequate hydration, the boy's condition improved, but chronic kidney disease was unfortunately inevitable.
Salmonella pyelonephritis has, according to our knowledge, not yet been described to be the main causative factor of ARF in previously healthy children, as was the case in our patient. Long-term antibiotic treatment of at least 6 weeks is probably a must in such patients, even though chronic kidney disease could not have been prevented.
儿童感染沙门氏菌后很少出现尿路感染、肾脓肿形成和急性肾衰竭(ARF)。我们报告了一例此前健康的青少年,他在感染沙门氏菌后发生 ARF 合并肾脓肿形成,我们认为急性沙门氏菌肾盂肾炎是导致 ARF 的主要病因,而不是文献中已经描述过的脱水、休克或横纹肌溶解。经过长时间的抗生素治疗和充分的水化,男孩的病情有所改善,但不幸的是仍不可避免地发展为慢性肾脏病。
据我们所知,沙门氏菌肾盂肾炎尚未被描述为此前健康儿童 ARF 的主要病因,而我们的患者就是这种情况。此类患者可能需要至少 6 周的长期抗生素治疗,尽管无法预防慢性肾脏病的发生。