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青年发病精神分裂症和 ADHD 的共病和非共病症状。

Shared and nonshared symptoms in youth-onset psychosis and ADHD.

机构信息

Institute of Child Development, University of Minnesota, Minneapolis, MN 55455, USA.

出版信息

J Atten Disord. 2010 Sep;14(2):121-31. doi: 10.1177/1087054709347434. Epub 2009 Oct 5.

Abstract

OBJECTIVE

We compared ratings of behavior and attention problems between youth-onset psychosis and ADHD, two disorders in which attentional impairments play a key role, and examined the effect of psychostimulant use on age of onset in psychosis.

METHOD

Parent and teacher ratings of behavioral problems and ADHD symptoms were collected using the Achenbach CBCL, TRF, and SNAP-IV Teacher Rating Scales on 42 participants with psychosis, 36 with ADHD and 57 controls (ages 8-19).

RESULTS AND CONCLUSIONS

Results suggested that academic, externalizing, and attention problems reflect symptoms shared between the disorders, whereas internalizing, social and thought problems reflect factors that differ between disorders. Furthermore, participants with psychosis who had been prescribed psychostimulants had a younger age of onset of psychotic symptoms than those who had not. This difference could reflect dissimilarities in symptom severity symptom between subgroups or potentially harmful effects of psychostimulants in individuals predisposed to develop psychosis.

摘要

目的

我们比较了青少年起病精神分裂症和 ADHD 这两种注意力损伤起关键作用的疾病之间的行为和注意力问题的评分,并研究了精神兴奋剂的使用对精神病发病年龄的影响。

方法

使用 Achenbach CBCL、TRF 和 SNAP-IV 教师评定量表,对 42 名精神分裂症患者、36 名 ADHD 患者和 57 名对照组(年龄 8-19 岁)的家长和教师进行了行为问题和 ADHD 症状的评定。

结果和结论

结果表明,学业、外化和注意力问题反映了两种疾病共有的症状,而内化、社会和思维问题则反映了两种疾病之间的差异因素。此外,服用精神兴奋剂的精神病患者的精神病症状发病年龄比未服用者小。这种差异可能反映了亚组之间症状严重程度的差异,或者精神兴奋剂在易患精神病的个体中可能产生有害影响。

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