在巴西和哥伦比亚流行的新型登革热 3 型病毒与旧的亚洲病毒密切相关。
New genotype of dengue type 3 virus circulating in Brazil and Colombia showed a close relationship to old Asian viruses.
机构信息
Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, Ribeirão Preto, São Paulo, Brasil.
出版信息
PLoS One. 2009 Oct 13;4(10):e7299. doi: 10.1371/journal.pone.0007299.
Dengue type 3 genotype V viruses have been recently detected in Brazil and Colombia. In this study, we described another Brazilian isolate belonging to this genotype. Phylogenetic analysis including dengue type 3 viruses isolated worldwide showed that Brazilian and Colombian viruses were closely related to viruses isolated in Asia more than two decades ago. The characteristic evolutionary pattern of dengue type 3 virus cannot explain the close similarity of new circulating viruses with old viruses. Further studies are needed to confirm the origin of the new dengue type III genotype circulating in Brazil and Colombia.
最近在巴西和哥伦比亚检测到了 3 型登革热病毒基因型 V 型。在本研究中，我们描述了另一种属于该基因型的巴西分离株。包括全球分离的 3 型登革热病毒在内的系统进化分析表明，巴西和哥伦比亚的病毒与二十多年前在亚洲分离的病毒密切相关。3 型登革热病毒的特征进化模式不能解释新流行病毒与旧病毒的密切相似性。需要进一步的研究来确认在巴西和哥伦比亚流行的新型 3 型登革热病毒的起源。
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