Kröber Thomas, Guerin Patrick
Institute of Biology, University of Neuchâtel, Neuchâtel, Switzerland.
ALTEX. 2007;24 Spec No:39-41.
An artificial feeding unit with a reinforced silicone membrane to replace host skin provides ticks with a perch over blood with a tick attachment rate of 75-100%. Some 5 mg of an acaricide like fipronil is sufficient to establish survival curves over different doses down to ppb levels in blood. This in vitro feeding assay for hard ticks is more advantageous than in vivo trials on animals.
一种带有强化硅胶膜以替代宿主皮肤的人工喂养装置能为蜱虫提供一个吸食血液的栖息处,蜱虫附着率为75%至100%。约5毫克的杀螨剂(如氟虫腈)就足以确定不同剂量直至血液中十亿分比水平的生存曲线。这种针对硬蜱的体外喂养试验比在动物身上进行的体内试验更具优势。