Kirkwood John M, Jukic Drazen M, Averbook Bruce J, Sender Leonard S
Department of Medicine, University of Pittsburgh School of Medicine, and Melanoma and Skin Cancer Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.
Semin Oncol. 2009 Oct;36(5):419-31. doi: 10.1053/j.seminoncol.2009.07.001.
The family practitioner, pediatrician, and dermatologist all have potential roles in the primary prevention, diagnosis, and treatment of localized thin melanomas. Surgical and medical oncologists are often involved when controversy arises over the nature of the skin lesion or whether sentinel lymph node (SLN) biopsies and adjuvant therapy are to be contemplated. This overview of melanoma will deal with the primary and nodal pathology, surgery, and medical therapy of melanoma in pediatric, adolescent, and young adult patients--and will raise areas of controversy that are only recently being addressed in databases of cases from this age group.
家庭医生、儿科医生和皮肤科医生在局限性薄型黑色素瘤的一级预防、诊断和治疗中都可能发挥作用。当对皮肤病变的性质或是否考虑进行前哨淋巴结(SLN)活检及辅助治疗存在争议时,外科肿瘤学家和医学肿瘤学家通常会参与其中。本黑色素瘤概述将涉及儿童、青少年和年轻成年患者黑色素瘤的原发灶和淋巴结病理、手术及药物治疗,并将提出一些争议领域,这些领域直到最近才在该年龄组的病例数据库中得到探讨。