Mowbrey Kevin, Dacks Joel B
Department of Cell Biology, University of Alberta, Edmonton, Canada T6G 2H7.
FEBS Lett. 2009 Dec 3;583(23):3738-45. doi: 10.1016/j.febslet.2009.10.025. Epub 2009 Oct 20.
Often considered a defining eukaryotic feature, the Golgi body is one of the most recognizable and functionally integrated cellular organelles. It is therefore surprising that some unicellular eukaryotes do not, at first glance, appear to possess Golgi stacks. Here we review the molecular evolutionary, genomic and cell biological evidence for Golgi bodies in these organisms, with the organelle likely present in some form in all cases. This, along with the overwhelming prevalence of stacked cisternae in most eukaryotes, implies that the ancestral eukaryote possessed a stacked Golgi body, with at least eight independent instances of Golgi unstacking in our cellular history.
高尔基体常被视为真核生物的一个决定性特征，是最容易识别且功能整合度最高的细胞器之一。因此，令人惊讶的是，一些单细胞真核生物乍一看似乎没有高尔基体堆叠结构。在此，我们回顾了这些生物中高尔基体的分子进化、基因组和细胞生物学证据，在所有情况下，该细胞器可能都以某种形式存在。这一点，再加上大多数真核生物中堆叠的扁平囊极为普遍，意味着原始真核生物拥有一个堆叠的高尔基体，在我们的细胞历史中，高尔基体至少有八个独立的解堆叠实例。
